Status: Bibliographieeintrag
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| Verfasst von: | Berg, Anna-Lena [VerfasserIn]  |
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| | Johannisson, A. [VerfasserIn] |
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| | Johansson, M. [VerfasserIn] |
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| | Hein, Andreas [VerfasserIn] |
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| | Berg, M. [VerfasserIn] |
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| | Dörries, Rüdiger [VerfasserIn] |
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| Titel: | Peripheral and intracerebral T cell immune response in cats naturally infected with Borna disease virus |
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| Verf.angabe: | A-L Berg, A. Johannisson, M. Johansson, A. Hein, M. Berg, R. Dörries |
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| E-Jahr: | 1999 |
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| Jahr: | 2 June 1999 |
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| Umfang: | 13 S. |
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| Fussnoten: | Gesehen am 30.06.2022 |
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| Titel Quelle: | Enthalten in: Veterinary immunology and immunopathology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1979 |
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| Jahr Quelle: | 1999 |
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| Band/Heft Quelle: | 68(1999), 2, Seite 241-253 |
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| ISSN Quelle: | 1873-2534 |
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| Abstract: | Borna disease virus (BDV) is a neurotropic agent with capacity to cause encephalomyelitis in a wide range of animal species, including horses and cats. Recent studies also point to a link between BDV and human neuropsychiatric disorders. The pathogenesis of Borna disease (BD) has been proposed to be immune-mediated, mainly through the effects of cytotoxic T cells. We used flow cytometric analysis in order to characterize the peripheral and intracerebral T cell immune response in cats naturally infected with BDV. Our results show the presence of two different CD8+ cell populations (CD8+low and CD8+high) in the blood, spleen and brain of these cats. In the brain, CD8+low cells predominated over CD8+high cells. Since CD8+low cells have been suggested to represent a non-MHC-restricted T cell population, the recruitment of such cells to the brains of BDV-infected cats could possibly be of importance for the clearance of virus from neurones. |
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| DOI: | doi:10.1016/S0165-2427(99)00030-6 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/S0165-2427(99)00030-6 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0165242799000306 |
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| | DOI: https://doi.org/10.1016/S0165-2427(99)00030-6 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Borna disease virus |
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| | Cats |
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| | CD8+ cells |
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| K10plus-PPN: | 1808683285 |
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| Verknüpfungen: | → Zeitschrift |
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Peripheral and intracerebral T cell immune response in cats naturally infected with Borna disease virus / Berg, Anna-Lena [VerfasserIn]; 2 June 1999 (Online-Ressource)
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