Revisiting nickel-catalyzed carbonylations

• Verfasst von: Lichtenberger, Niels [VerfasserIn]
• Verfasst von: Menche, Maximilian [VerfasserIn]
• Verfasst von: Rück, Katharina [VerfasserIn]
• Verfasst von: Paciello, Rocco [VerfasserIn]
• Verfasst von: Schäfer, Ansgar [VerfasserIn]
• Verfasst von: Comba, Peter [VerfasserIn]
• Verfasst von: Hashmi, A. Stephen K. [VerfasserIn]
• Verfasst von: Schaub, Thomas [VerfasserIn]
• Titel: Revisiting nickel-catalyzed carbonylations
• Titelzusatz: (unexpected) observation of substrate-dependent mechanistic differences
• Verf.angabe: Niels Lichtenberger, Maximilian Menche, Katharina S.L. Rück, Rocco Paciello, Ansgar Schäfer, Peter Comba, A. Stephen K. Hashmi, and Thomas Schaub
• E-Jahr: 2022
• Jahr: 5 May 2022
• Umfang: 13 S.
• Fussnoten: Gesehen am 06.07.2022
• Titel Quelle: Enthalten in: Organometallics
• Ort Quelle: Washington, DC : ACS Publ., 1982
• Jahr Quelle: 2022
• Band/Heft Quelle: 41(2022), 10, Seite 1184-1196
• ISSN Quelle: 1520-6041
• DOI: doi:10.1021/acs.organomet.2c00090
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1809308550

Abstract

The (hydroxy)carbonylation of tertiary aliphatic alcohols and their corresponding olefins with a Ni-based catalyst system is investigated. This study builds on a previous mechanistic investigation into the Ni-catalyzed carbonylation of alcohols. The findings differed from what could be explained with the previously reported mechanisms, prompting this in-depth mechanistic study. Combined experimental and quantum chemical efforts are crucial for the rationalization of the observed reactivities and ultimately help reveal another isobutene-based catalytic pathway, accessible with these substrates. This study further expands the knowledge about Ni-catalyzed carbonylation reactions, which have been known for more than 70 years but were scarcely studied in detail from a mechanistic point of view.