| Online-Ressource |
Verfasst von: | Hoffmann, Stefan Heinrich [VerfasserIn]  |
| Begovatz, Paul [VerfasserIn]  |
| Nagel, Armin Michael [VerfasserIn]  |
| Umathum, Reiner [VerfasserIn]  |
| Schommer, Kai [VerfasserIn]  |
| Bachert, Peter [VerfasserIn]  |
| Bock, Michael [VerfasserIn]  |
Titel: | A measurement setup for direct 17O MRI at 7 T |
Verf.angabe: | Stefan H. Hoffmann, Paul Begovatz, Armin M. Nagel, Reiner Umathum, Kai Schommer, Peter Bachert, and Michael Bock |
E-Jahr: | 2011 |
Jahr: | [October 2011] |
Umfang: | 7 S. |
Illustrationen: | Illustrationen |
Fussnoten: | First published: 09 March 2011 ; Die 17 im Titel ist hochgestellt ; Gesehen am 11.07.2022 |
Titel Quelle: | Enthalten in: Magnetic resonance in medicine |
Ort Quelle: | New York, NY [u.a.] : Wiley-Liss, 1984 |
Jahr Quelle: | 2011 |
Band/Heft Quelle: | 66(2011), 4 vom: Okt., Seite 1109-1115 |
ISSN Quelle: | 1522-2594 |
Abstract: | An efficient breathing system was designed for direct 17O MRI to perform oxygen metabolism studies of the human brain. The breathing system consists of a demand oxygen delivery device for 17O2 supply and a custom-built re-breathing circuit with pneumatic switching valve. To efficiently deliver the 17O gas to the alveoli of the lungs, the system applies short gas pulses upon an inspiration trigger via a nasal cannula. During and after 17O2 administration, the exhaled gas volumes are stored and filtered in the re-breathing section to make the most efficient use of the rare 17O gas. In an inhalation experiment, 2.2 ± 0.1 L of 70%-enriched 17O2 were administered to a healthy volunteer and direct 17O MRI was performed for a total imaging time of 38 min with a temporal resolution of 50 s per 3D data set. Mapping of the maximum signal increase was carried out showing regional variations of oxygen concentration of up to 30% over the natural abundance of 17O water. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc. |
DOI: | doi:10.1002/mrm.22871 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1002/mrm.22871 |
| Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.22871 |
| DOI: https://doi.org/10.1002/mrm.22871 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | brain metabolism |
| cerebral metabolic rate of oxygen consumption (CMRO2) |
| direct 17O MRI |
| high field MRI |
| non-proton MRI |
| oxygen-17 |
K10plus-PPN: | 1809689139 |
Verknüpfungen: | → Zeitschrift |
¬A¬ measurement setup for direct 17O MRI at 7 T / Hoffmann, Stefan Heinrich [VerfasserIn]; [October 2011] (Online-Ressource)