Molecules, cells and networks involved in processing olfactory stimuli in the mouse olfactory bulb

• Verfasst von: Kuner, Thomas [VerfasserIn]
• Verfasst von: Schaefer, Andreas T. [VerfasserIn]
• Titel: Molecules, cells and networks involved in processing olfactory stimuli in the mouse olfactory bulb
• Verf.angabe: T. Kuner, A. Schaefer
• Jahr: 2011
• Umfang: 7 S.
• Fussnoten: Elektronische Reproduktion der Druckausgabe ; Gesehen am 11.07.2022
• Titel Quelle: Enthalten in: e-Neuroforum
• Ort Quelle: Heidelberg : Spektrum Akademischer Verlag, 2010
• Jahr Quelle: 2011
• Band/Heft Quelle: 17(2011), 3, Seite 61-67
• ISSN Quelle: 1868-856X
• DOI: doi:10.1007/s13295-011-0019-0
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1809702518

Abstract

How sensory stimuli are processed by neural networks is a key question of neurosci­ence. Olfactory conditioning experiments in mice demonstrated that odour processing is fast and stimulus-dependent. Selective ge­netic perturbation of the inhibitory circuitry in the first relay station of olfactory processing, the olfactory bulb, altered such discrim­ination times, with increased inhibition accelerating and decreased inhibition slowing down odour discrimination. This illustrates that inhibition fulfils a key role in sensory processing.