Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Kurz, Jochen [VerfasserIn]   i
 Eberle, Florian [VerfasserIn]   i
 Graumann, Tobias [VerfasserIn]   i
 Kaschel, Mariel-Esther [VerfasserIn]   i
 Sähr, Aline [VerfasserIn]   i
 Neumann, Frank [VerfasserIn]   i
 Dalpke, Alexander [VerfasserIn]   i
 Erdinger, Lothar [VerfasserIn]   i
Titel:Inactivation of LPS and RNase A on photocatalytically active surfaces
Verf.angabe:Jochen Kurz, Florian Eberle, Tobias Graumann, Mariel-Esther Kaschel, Aline Sähr, Frank Neumann, Alexander H. Dalpke, Lothar Erdinger
E-Jahr:2011
Jahr:16 July 2011
Umfang:6 S.
Fussnoten:Gesehen am 11.07.2022
Titel Quelle:Enthalten in: Chemosphere
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 1972
Jahr Quelle:2011
Band/Heft Quelle:84(2011), 9, Seite 1188-1193
ISSN Quelle:1879-1298
Abstract:TiO2 coated surfaces are able to generate highly reactive oxidizing species under mild UV-A light exposure in the presence of water and oxygen. We have demonstrated that these radicals are sufficient to eliminate different pathogenic bacteria, by breaking their cell walls. The photocatalytic activity of surfaces coated with titanium dioxide offers therefore an alternative possibility of disinfection. However, restriction of bacterial growth does not protect surfaces from bacterial derived contaminations, such as endotoxins. Lipopolysaccharides (LPS) and Ribonuclease A (RNAse A) represent the two most abundant contaminations, causing severe problems in biomedical and immunological research as well as in the pharmaceutical industry. Due to their high stability, complete removal of these contaminants is technically challenging. Using irradiated TiO2 coated glass plates, RNAse A and LPS containing contaminations could be completely inactivated. By establishing highly sensitive immuno-based assays, destruction of the contaminants was quantified and shown to be independent of the initial concentrations, following a zero-order reaction. Exposure for 96h resulted in a reduction of 11ng of LPS and 7 units of RNase A cm−2 surface. These amounts are comparable to contamination levels found under standard working conditions. Titanium dioxide coatings provide therefore a powerful tool for auto-disinfection and self-cleaning of surfaces.
DOI:doi:10.1016/j.chemosphere.2011.06.048
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.chemosphere.2011.06.048
 Volltext: https://www.sciencedirect.com/science/article/pii/S0045653511006916
 DOI: https://doi.org/10.1016/j.chemosphere.2011.06.048
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Endotoxin
 Endotoxin degradation
 Lipopolysaccharide
 Photocatalysis
 Photocatalytic oxidation
 Titanium dioxide (TiO)
K10plus-PPN:1809715059
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68940056   QR-Code
zum Seitenanfang