Status: Bibliographieeintrag
Standort: ---
Exemplare:
---
| Online-Ressource |
Verfasst von: | Hertle, Anna M. [VerfasserIn]  |
| Bading, Hilmar [VerfasserIn]  |
Titel: | Calcium signaling in synapse-to-nucleus communication |
Verf.angabe: | Anna M. Hagenston and Hilmar Bading |
Jahr: | 2011 |
Umfang: | 33 S. |
Fussnoten: | Gesehen am 27.07.2022 |
Titel Quelle: | Enthalten in: Cold Spring Harbor perspectives in biology |
Ort Quelle: | Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, 2009 |
Jahr Quelle: | 2011 |
Band/Heft Quelle: | 3(2011), 11, Artikel-ID a004564, Seite 1-33- |
ISSN Quelle: | 1943-0264 |
Abstract: | Changes in the intracellular concentration of calcium ions in neurons are involved in neurite growth, development, and remodeling, regulation of neuronal excitability, increases and decreases in the strength of synaptic connections, and the activation of survival and programmed cell death pathways. An important aspect of the signals that trigger these processes is that they are frequently initiated in the form of glutamatergic neurotransmission within dendritic trees, while their completion involves specific changes in the patterns of genes expressed within neuronal nuclei. Accordingly, two prominent aims of research concerned with calcium signaling in neurons are determination of the mechanisms governing information conveyance between synapse and nucleus, and discovery of the rules dictating translation of specific patterns of inputs into appropriate and specific transcriptional responses. In this article, we present an overview of the avenues by which glutamatergic excitation of dendrites may be communicated to the neuronal nucleus and the primary calcium-dependent signaling pathways by which synaptic activity can invoke changes in neuronal gene expression programs. |
DOI: | doi:10.1101/cshperspect.a004564 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1101/cshperspect.a004564 |
| Volltext: http://cshperspectives.cshlp.org/content/3/11/a004564 |
| DOI: https://doi.org/10.1101/cshperspect.a004564 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1811827217 |
Verknüpfungen: | → Zeitschrift |
Calcium signaling in synapse-to-nucleus communication / Hertle, Anna M. [VerfasserIn]; 2011 (Online-Ressource)
68947412