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| Verfasst von: | Arvanitaki, Alexandra [VerfasserIn]  |
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| | Gatzoulis, Michael A. [VerfasserIn] |
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| | Opotowsky, Alexander R. [VerfasserIn] |
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| | Khairy, Paul [VerfasserIn] |
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| | Dimopoulos, Konstantinos [VerfasserIn] |
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| | Diller, Gerhard-Paul [VerfasserIn] |
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| | Giannakoulas, George [VerfasserIn] |
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| | Brida, Margarita [VerfasserIn] |
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| | Griselli, Massimo [VerfasserIn] |
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| | Grünig, Ekkehard [VerfasserIn] |
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| | Montanaro, Claudia [VerfasserIn] |
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| | Alexander, Peter David [VerfasserIn] |
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| | Ameduri, Rebecca [VerfasserIn] |
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| | Mulder, Barbara J. M. [VerfasserIn] |
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| | D’Alto, Michele [VerfasserIn] |
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| Titel: | Eisenmenger syndrome |
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| Titelzusatz: | JACC state-of-the-art review |
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| Verf.angabe: | Alexandra Arvanitaki, Michael A. Gatzoulis, Alexander R. Opotowsky, Paul Khairy, Konstantinos Dimopoulos, Gerhard-Paul Diller, George Giannakoulas, Margarita Brida, Massimo Griselli, Ekkehard Grünig, Claudia Montanaro, Peter David Alexander, Rebecca Ameduri, Barbara J.M. Mulder, Michele D’Alto |
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| E-Jahr: | 2022 |
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| Jahr: | 21 March 2022 |
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| Umfang: | 16 S. |
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| Fussnoten: | Gesehen am 08.08.2022 |
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| Titel Quelle: | Enthalten in: American College of CardiologyJournal of the American College of Cardiology |
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| Ort Quelle: | New York, NY : Elsevier, 1983 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 79(2022), 12, Seite 1183-1198 |
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| ISSN Quelle: | 1558-3597 |
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| Abstract: | Although major breakthroughs in the field of pediatric cardiology, cardiac surgery, intervention, and overall care improved the outlook of congenital heart disease, Eisenmenger syndrome (ES) is still encountered and remains a complex clinical entity with multisystem involvement, including secondary erythrocytosis, increased thrombotic and bleeding diathesis, high arrhythmogenic risk, progressive heart failure, and premature death. Clearly, care for ES is best delivered in multidisciplinary expert centers. In this review, we discuss the considerable recent progress in understanding the complex pathophysiology of ES, means of prognostication, and improvement in clinical outcomes achieved with pulmonary arterial hypertension-targeted therapies. Additionally, we delineate areas of uncertainty in various aspects of care, discuss gaps in current evidence, and review current status in less privileged countries and propose initiatives to reduce disease burden. Finally, we propose the application of emerging technologies to enhance the delivery and quality of health care related to ES and beyond. |
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| DOI: | doi:10.1016/j.jacc.2022.01.022 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.jacc.2022.01.022 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0735109722001887 |
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| | DOI: https://doi.org/10.1016/j.jacc.2022.01.022 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | congenital heart disease |
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| | Eisenmenger syndrome |
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| | multisystem involvement |
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| | pulmonary arterial hypertension |
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| | risk stratification |
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| | targeted pulmonary arterial hypertension therapy |
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| K10plus-PPN: | 1813405433 |
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| Verknüpfungen: | → Zeitschrift |
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Eisenmenger syndrome / Arvanitaki, Alexandra [VerfasserIn]; 21 March 2022 (Online-Ressource)
