Renal salt wasting as part of dysautonomia in Guillain-Barré syndrome

• Verfasst von: Lenhard, Thorsten [VerfasserIn]
• Verfasst von: Grimm, Christiane [VerfasserIn]
• Verfasst von: Ringleb, Peter A. [VerfasserIn]
• Titel: Renal salt wasting as part of dysautonomia in Guillain-Barré syndrome
• Verf.angabe: T. Lenhard, C. Grimm, P.A. Ringleb
• Jahr: 2011
• Umfang: 3 S.
• Fussnoten: Published online first 22 August 2010 ; Gesehen am 16.08.2022
• Titel Quelle: Enthalten in: Journal of neurology, neurosurgery, and psychiatry
• Ort Quelle: London : BMJ Publishing Group, 1944
• Jahr Quelle: 2011
• Band/Heft Quelle: 82(2011), 9, Seite 1051-1053
• ISSN Quelle: 1468-330X
• DOI: doi:10.1136/jnnp.2009.192369
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Hyponatraemia
• Sach-SW: intensive care
• Sach-SW: radiculopathy
• Sach-SW: respiratory insufficiency
• K10plus-PPN: 1814393056

Abstract

Cerebral salt-wasting syndrome and the syndrome of inappropriate antidiuresis (SIAD) are the most important causes of non-iatrogenic hyponatraemia that can significantly complicate various brain diseases. Salt wasting without an underlying CNS disease may have been disregarded so far by clinicians and has been described as renal salt-wasting (RSW) in patients as drug side effect (eg, cisplatin), in older people with various common diseases (eg, hip fracture, pulmonary infections) and other sporadic conditions. In Guillain-Barré Syndrome (GBS), however, hyponatraemia has been described mainly as SIAD. However, symptoms of hyponatraemia rarely develop in GBS. Here, we report on a woman with GBS with dominant symptoms of dysautonomia and moderate severe hyponatraemia. We could identify RSW as part of the autonomic dysfunction that significantly contributed to disease worsening.