| |  Online-Ressource |
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| Verfasst von: | Singer, Shereen [VerfasserIn]  |
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| | Schneider, Stefan W. [VerfasserIn] |
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| | Henzler, Thomas [VerfasserIn] |
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| | Desch, Anna [VerfasserIn] |
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| | Weiß, Christel [VerfasserIn] |
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| | Haubenreisser, Holger [VerfasserIn] |
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| | Goerdt, Sergij [VerfasserIn] |
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| | Morelli, John N. [VerfasserIn] |
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| | Utikal, Jochen [VerfasserIn] |
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| | Schönberg, Stefan [VerfasserIn] |
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| | Riffel, Julia [VerfasserIn] |
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| Titel: | Incidence of pulmonary embolism and impact on mortality in patients with malignant melanoma |
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| Verf.angabe: | Shereen Rennebaum, Stefan W. Schneider, Thomas Henzler, Anna Desch, Christel Weiß, Holger Haubenreisser, Sergij Goerdt, John N. Morelli, Jochen S. Utikal, Stefan O. Schoenberg, Julia Riffel |
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| Jahr: | 2022 |
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| Umfang: | 5 S. |
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| Fussnoten: | Available online 30 December 2021 ; Gesehen am 30.08.2022 |
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| Titel Quelle: | Enthalten in: Clinical imaging |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1989 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 83(2022), Seite 72-76 |
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| ISSN Quelle: | 1873-4499 |
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| Abstract: | PURPOSE: Pulmonary embolism (PE) occurs frequently in patients with malignant melanoma (MM). The aim of this study is to determine the incidence of PE in patients with MM and to assess the clinical characteristics and mortality of MM patients with PE. - MATERIAL AND METHODS: Medical records from 381 MM patients who underwent contrast-enhanced computed tomography were evaluated. Imaging parameters including location of PE and measurements of right heart dysfunction and clinical parameters including D-Dimer levels, local and distant tumor stage and time of death were analyzed. - RESULTS: PE was found in 23/381 (6%) MM patients, whereby 17/23 (74%) were detected incidentally and only 6/23 (26%) were symptomatic. The presence of PE significantly correlated with elevated D-Dimers (p < 0.001), right ventricular dysfunction (p = 0.04), higher local tumor stage (≥T3) (p = 0.05), presence of visceral (p = 0.02) or cerebral metastases (p = 0.03) and increased mortality (p = 0.05). Further, patients with central PE showed an increased mortality compared to peripheral PE (p = 0.03), but no correlation was found between the localization of PE and the occurrence of clinical symptoms (p = 0.36). - CONCLUSION: PE in patients with MM often occurs without clinical symptoms and is indicative for advanced disease and a poorer prognosis. |
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| DOI: | doi:10.1016/j.clinimag.2021.12.012 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.clinimag.2021.12.012 |
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| | DOI: https://doi.org/10.1016/j.clinimag.2021.12.012 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Clinical symptoms |
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| | Computed tomography |
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| | Humans |
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| | Incidence |
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| | Malignant melanoma |
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| | Melanoma |
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| | Mortality |
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| | Pulmonary embolism |
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| | Pulmonary Embolism |
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| | Retrospective Studies |
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| | Ventricular Dysfunction, Right |
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| K10plus-PPN: | 1815392908 |
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| Verknüpfungen: | → Zeitschrift |
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Incidence of pulmonary embolism and impact on mortality in patients with malignant melanoma / Singer, Shereen [VerfasserIn]; 2022 (Online-Ressource)
