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Status: Bibliographieeintrag

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Verfasst von:Krüchten, Ricarda von [VerfasserIn]   i
 Lorbeer, Roberto [VerfasserIn]   i
 Müller-Peltzer, Katharina [VerfasserIn]   i
 Rospleszcz, Susanne [VerfasserIn]   i
 Storz, Corinna [VerfasserIn]   i
 Askani, Esther [VerfasserIn]   i
 Kulka, Charlotte [VerfasserIn]   i
 Schuppert, Christopher [VerfasserIn]   i
 Rathmann, Wolfgang [VerfasserIn]   i
 Peters, Annette [VerfasserIn]   i
 Bamberg, Fabian [VerfasserIn]   i
 Schlett, Christopher L. [VerfasserIn]   i
 Mujaj, Blerim [VerfasserIn]   i
Titel:Association between adipose tissue depots and dyslipidemia
Titelzusatz:the KORA-MRI population-based study
Verf.angabe:Ricarda von Krüchten, Roberto Lorbeer, Katharina Müller-Peltzer, Susanne Rospleszcz, Corinna Storz, Esther Askani, Charlotte Kulka, Christopher Schuppert, Wolfgang Rathmann, Annette Peters, Fabian Bamberg, Christopher L. Schlett and Blerim Mujaj
E-Jahr:2022
Jahr:14 February 2022
Umfang:12 S.
Fussnoten:Gesehen am 02.09.2022
Titel Quelle:Enthalten in: Nutrients
Ort Quelle:Basel : MDPI, 2009
Jahr Quelle:2022
Band/Heft Quelle:14(2022), 4, Artikel-ID 797, Seite 1-12
ISSN Quelle:2072-6643
Abstract:Obesity increases the risk of cardiovascular diseases (CVD), however, whether adipose tissue relates to dyslipidemia, and consequently to cardiovascular events remains unknown. Thus, we investigated the association of adipose tissue with circulating lipoproteins and triglycerides (TG) in subjects without CVD. 384 participants from the KORA-MRI study (mean age 56.2 ± 9.2 years; 41.9% female) underwent whole-body 3T-MRI. Visceral (VAT) and subcutaneous adipose tissue (SAT) derived from T1-DIXON-sequence using a semi-automatic algorithm. Total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and TG were measured. Linear regression was applied to examine the relationships between adipose tissue, circulating lipoproteins, and TG, adjusting for risk factors. VAT was associated with total cholesterol (per SD increase) (ß = 0.39, p < 0.001). Total adipose tissue (TAT) and VAT were inversely associated with HDL (ß = -0.09, p = 0.009; ß = -0.14, p < 0.001), and positively associated with LDL (ß = 0.32, p < 0.001; ß = 0.37, p < 0.001). All adipose tissues were associated with TG (ß = 0.20, p < 0.001; ß = 0.27, p < 0.001; ß = 0.11, p = 0.004). Stratified analysis by sex and body mass index (BMI) was confirmatory in women and in individuals with BMI < 30. Our results suggest that adipose tissue plays an important role in increasing CVD risk independent of BMI, whereas gender imbalance may be explained by accurate characterization and quantification of adipose tissue.
DOI:doi:10.3390/nu14040797
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.3390/nu14040797
 DOI: https://doi.org/10.3390/nu14040797
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:adipose tissue
 Adipose Tissue
 Aged
 Body Mass Index
 Dyslipidemias
 Female
 HDL-cholesterol
 Humans
 Intra-Abdominal Fat
 LDL-cholesterol
 magnetic resonance imaging
 Magnetic Resonance Imaging
 Male
 Middle Aged
 population-based cohort
 Subcutaneous Fat
 total cholesterol
 triglycerides
K10plus-PPN:1815694807
Verknüpfungen:→ Zeitschrift

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