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| Verfasst von: | Koch, Vitali [VerfasserIn]  |
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| | Grünewald, Leon David [VerfasserIn] |
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| | Albrecht, Moritz H. [VerfasserIn] |
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| | Eichler, Katrin [VerfasserIn] |
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| | Gruber-Rouh, Tatjana [VerfasserIn] |
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| | Yel, Ibrahim [VerfasserIn] |
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| | Alizadeh, Leona Soraja [VerfasserIn] |
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| | Mahmoudi, Scherwin [VerfasserIn] |
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| | Scholtz, Jan-Erik [VerfasserIn] |
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| | Martin, Simon [VerfasserIn] |
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| | Lenga, Lukas [VerfasserIn] |
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| | Vogl, Thomas J. [VerfasserIn] |
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| | Nour-Eldin, Nour-Eldin Abdelrehim [VerfasserIn] |
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| | Bienenfeld, Florian [VerfasserIn] |
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| | Hammerstingl, Renate [VerfasserIn] |
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| | Graf, Christiana [VerfasserIn] |
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| | Sommer, Christof-Matthias [VerfasserIn] |
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| | Hardt, Stefan [VerfasserIn] |
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| | Mazziotti, Silvio [VerfasserIn] |
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| | Ascenti, Giorgio [VerfasserIn] |
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| | Versace, Giovanni Antonio [VerfasserIn] |
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| | D'Angelo, Tommaso [VerfasserIn] |
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| | Booz, Christian [VerfasserIn] |
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| Titel: | Lung opacity and coronary artery calcium score |
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| Titelzusatz: | a combined tool for risk stratification and outcome prediction in COVID-19 patients |
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| Verf.angabe: | Vitali Koch, MD, Leon D. Gruenewald, MD, Moritz H. Albrecht, MD, Katrin Eichler, MD, Tatjana Gruber-Rouh, MD, Ibrahim Yel, MD, Leona S. Alizadeh, MD, Scherwin Mahmoudi, MD, Jan-Erik Scholtz, MD, Simon S. Martin, MD, Lukas Lenga, MD, Thomas J. Vogl, MD, Nour-Eldin A. Nour-Eldin, MD, Florian Bienenfeld, MD, Renate M. Hammerstingl, MD, Christiana Graf, MD, Christof M. Sommer, MD, Stefan E. Hardt, MD, Silvio Mazziotti, MD, Giorgio Ascenti, MD, Giovanni Antonio Versace, MD, Tommaso D’Angelo, MD, Christian Booz, MD |
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| E-Jahr: | 2022 |
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| Jahr: | June 2022 |
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| Umfang: | 10 S. |
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| Fussnoten: | Online veröffenticht: 28. Februar 2022 ; Gesehen am 06.09.2022 |
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| Titel Quelle: | Enthalten in: Academic radiology |
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| Ort Quelle: | Philadelphia, PA [u.a.] : Elsevier, 1994 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 29(2022), 6 vom: Juni, Seite 861-870 |
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| ISSN Quelle: | 1878-4046 |
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| Abstract: | Purpose - To assess and correlate pulmonary involvement and outcome of SARS-CoV-2 pneumonia with the degree of coronary plaque burden based on the CAC-DRS classification (Coronary Artery Calcium Data and Reporting System). - Methods - This retrospective study included 142 patients with confirmed SARS-CoV-2 pneumonia (58 ± 16 years; 57 women) who underwent non-contrast CT between January 2020 and August 2021 and were followed up for 129 ± 72 days. One experienced blinded radiologist analyzed CT series for the presence and extent of calcified plaque burden according to the visual and quantitative HU-based CAC-DRS Score. Pulmonary involvement was automatically evaluated with a dedicated software prototype by another two experienced radiologists and expressed as Opacity Score. - Results - CAC-DRS Scores derived from visual and quantitative image evaluation correlated well with the Opacity Score (r=0.81, 95% CI 0.76-0.86, and r=0.83, 95% CI 0.77-0.89, respectively; p<0.0001) with higher correlation in severe than in mild stage SARS-CoV-2 pneumonia (p<0.0001). Combined, CAC-DRS and Opacity Scores revealed great potential to discriminate fatal outcomes from a mild course of disease (AUC 0.938, 95% CI 0.89-0.97), and the need for intensive care treatment (AUC 0.801, 95% CI 0.77-0.83). Visual and quantitative CAC-DRS Scores provided independent prognostic information on all-cause mortality (p=0.0016 and p<0.0001, respectively), both in univariate and multivariate analysis. - Conclusions - Coronary plaque burden is strongly correlated to pulmonary involvement, adverse outcome, and death due to respiratory failure in patients with SARS-CoV-2 pneumonia, offering great potential to identify individuals at high risk. |
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| DOI: | doi:10.1016/j.acra.2022.02.019 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.acra.2022.02.019 |
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| | kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S1076633222001295 |
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| | DOI: https://doi.org/10.1016/j.acra.2022.02.019 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | CAC-DRS Score |
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| | Computed Tomography |
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| | Coronary Heart Disease |
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| | Coronary Plaque Burden |
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| | SARS-CoV-2 Pneumonia |
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| K10plus-PPN: | 1815839406 |
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| Verknüpfungen: | → Zeitschrift |
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Lung opacity and coronary artery calcium score / Koch, Vitali [VerfasserIn]; June 2022 (Online-Ressource)
