Small renal cell carcinoma

• Verfasst von: Pahernik, Sascha [VerfasserIn]
• Verfasst von: Huber, Johannes [VerfasserIn]
• Verfasst von: Pfitzenmaier, Jesco [VerfasserIn]
• Verfasst von: Haferkamp, Axel [VerfasserIn]
• Verfasst von: Hohenfellner, Markus [VerfasserIn]
• Titel: Small renal cell carcinoma
• Titelzusatz: oncological outcome with tumour size
• Verf.angabe: Sascha Pahernik, Johannes Huber, Jesco Pfitzenmaier, Axel Haferkamp & Markus Hohenfellner
• E-Jahr: 2011
• Jahr: 24 October 2011
• Umfang: 4 S.
• Fussnoten: Gesehen am 06.09.2022
• Titel Quelle: Enthalten in: Scandinavian journal of urology and nephrology
• Ort Quelle: Abingdon : Taylor & Francis, 1967
• Jahr Quelle: 2011
• Band/Heft Quelle: 45(2011), 6, Seite 432-435
• ISSN Quelle: 1651-2065
• DOI: doi:10.3109/00365599.2011.621143
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Adolescent
• Sach-SW: Adult
• Sach-SW: Aged
• Sach-SW: Aged, 80 and over
• Sach-SW: Carcinoma, Renal Cell
• Sach-SW: Disease Progression
• Sach-SW: Female
• Sach-SW: Humans
• Sach-SW: Kaplan-Meier Estimate
• Sach-SW: Kidney Neoplasms
• Sach-SW: Male
• Sach-SW: Middle Aged
• Sach-SW: Neoplasm Metastasis
• Sach-SW: Neoplasm Staging
• Sach-SW: Prognosis
• Sach-SW: Statistics, Nonparametric
• Sach-SW: Tumor Burden
• Sach-SW: Young Adult
• K10plus-PPN: 1815878452

Abstract

OBJECTIVE: The aim of the study was to analyse oncological outcomes of patients with renal cell carcinoma (RCC) up to 4 cm in diameter. - MATERIAL AND METHODS: A consecutive series of 396 patients with small RCC was analysed. Tumours were stratified by diameter into three groups: 2 cm (n = 68) for tumours up to 2 cm, 3 cm (n = 172) for tumours between 2.1 and 3.0 cm, and 4 cm (n = 156) for tumours between 3.1 and 4.0 cm in diameter. - RESULTS: Tumour stages were distributed into pT1a in 95.6%, 91.9% and 87.0% and into pT3 in 4.4%, 8.1% and 13.0% for the 2 cm, 3 cm and 4 cm groups, respectively. Metastases at the time of diagnosis were found in 2.9% (n = 2), 7.5% (n = 13) and 9.1% (n = 14) of patients in the 2 cm, 3 cm and 4 cm groups, respectively. The tumour-specific survival was 100%, 96.9% and 94.6% at 1 year, 97.5%, 90.3% and 87.5% at 5 years and 97.5%, 87.3% and 84.1% at 10 years for the 2 cm, 3 cm and 4 cm groups, respectively (p < 0.05). - CONCLUSIONS: Negative prognostic features as well as worse oncological outcome increase with tumour diameter above 2 cm. These data have important implications when considering active surveillance of small renal tumours.