Computer-based liver volumetry in the liver perfusion simulator

• Verfasst von: Müller, Sascha A. [VerfasserIn]
• Verfasst von: Pianka, Frank [VerfasserIn]
• Verfasst von: Schöbinger, Maximilian [VerfasserIn]
• Verfasst von: Mehrabi, Arianeb [VerfasserIn]
• Verfasst von: Fonouni, Hamidreza [VerfasserIn]
• Verfasst von: Radeleff, Boris [VerfasserIn]
• Verfasst von: Meinzer, Hans-Peter [VerfasserIn]
• Verfasst von: Schmied, Bruno [VerfasserIn]
• Titel: Computer-based liver volumetry in the liver perfusion simulator
• Verf.angabe: Sascha Arian Müller, M.D., Frank Pianka, M.D., Max Schöbinger, Arianeb Mehrabi, M.D., Hamid Fonouni, M.D., Boris Radeleff, M.D., Hans-Peter Meinzer, Prof., and Bruno M. Schmied, M.D.
• Jahr: 2011
• Umfang: 7 S.
• Fussnoten: First published online: 20 March 2010 ; Gesehen am 14.09.2022
• Titel Quelle: Enthalten in: Journal of surgical research
• Ort Quelle: Orlando, Fla. : Academic Press, 1961
• Jahr Quelle: 2011
• Band/Heft Quelle: 171(2011), 1 vom: Nov., Seite 87-93
• ISSN Quelle: 1095-8673
• DOI: doi:10.1016/j.jss.2010.02.038
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Heidelberg algorithm
• Sach-SW: liver interventions
• Sach-SW: liver perfusion
• Sach-SW: liver perfusion simulator
• Sach-SW: liver volumetry
• Sach-SW: multislice CT scan
• K10plus-PPN: 1816642754

Abstract

Background - An exact preoperative liver volume calculation is important prior to liver surgery and living-related liver transplantation. However, CT or MRI assessment of preoperative liver volume is associated with an estimation error of 1.2% to 36%, and little data is available on its accuracy on the segmental level. The aim of this study was to validate arterial and portal venous flow rates and gain information on liver volumetry, including liver segments, in the liver perfusion simulator and compare it to in vivo measurements in a porcine model. - Material and Methods - The arterial and portal venous flow rates and liver volumes of 10 pigs were measured in vivo and compared with the flow rates and volumes ex vivo. CT scans were performed and the volume of the liver and its lobes calculated by water displacement or computer-assistance based on the CT scans. The right lateral lobe was plasticized and reconstructed for the volume calculation. - Results - In the liver perfusion simulator, arterial and portal venous flow rates comparable to the in vivo rates were achieved. The liver volume had a mean difference of 10.3% between in vivo and ex vivo measurements. In the liver perfusion simulator, the mean deviation in liver volume between the computer calculation and water displacement was 2.8%. On the segmental level, the Heidelberg algorithm provided an accuracy of 97.7%. - Conclusion - The liver perfusion simulator is an excellent device for studies in liver perfusion and volumetry. Furthermore, the simulator is applicable for teaching and performing interventions and surgeries in livers.