| |  Online-Ressource |
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| Verfasst von: | Hauswald, Henrik [VerfasserIn]  |
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| | Milker-Zabel, Stefanie [VerfasserIn] |
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| | Sterzing, Florian [VerfasserIn] |
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| | Schlegel, Wolfgang [VerfasserIn] |
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| | Debus, Jürgen [VerfasserIn] |
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| | Zabel-du Bois, Angelika [VerfasserIn] |
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| Titel: | Repeated linac-based radiosurgery in high-grade cerebral arteriovenous-malformations (AVM) Spetzler-Martin grade III to IV previously treated with radiosurgery |
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| Verf.angabe: | Henrik Hauswald, Stefanie Milker-Zabel, Florian Sterzing, Wolfgang Schlegel, Juergen Debus, Angelika Zabel-du Bois |
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| E-Jahr: | 2011 |
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| Jahr: | [February 2011] |
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| Umfang: | 6 S. |
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| Fussnoten: | Gesehen am 23.09.2022 |
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| Titel Quelle: | Enthalten in: Radiotherapy and oncology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1983 |
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| Jahr Quelle: | 2011 |
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| Band/Heft Quelle: | 98(2011), 2 vom: Feb., Seite 217-222 |
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| ISSN Quelle: | 1879-0887 |
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| Abstract: | Background - Aim was to access outcome and toxicity of repeated linac-based radiosurgery in incompletely obliterated cerebral AVM. - Patients and methods - Between 1998 and 2008, 11 patients were treated with repeated radiosurgery. The median dose to the 80%-isodose was 15Gy (range, 12-18Gy). During initial radiosurgery the median dose was 18Gy (range, 9-22Gy). - Results - The median time interval between initial radiosurgery and re-treatment was 9years (range, 4-16years). The median follow-up was 26months (range, 2-115months). Treatment response was seen in 8 patients (89%). Complete (partial) obliteration was achieved in 5 (3) patients (56%, 33%, respectively).The median time to complete obliteration was 26months (range, 5-45months). Pre-existing neurological symptoms improved in 2 patients (18%), were stable in 7 patients (64%) and worsened in 2 patients (18%). Prevalence of intracranial hemorrhage was 9% (1/11). Post-re-treatment intracranial hemorrhage rate was 2.7% (1/38years at risk). During follow-up, no secondary malignancies or toxicity>grade III were observed. - Conclusion - Repeated linac-based radiosurgery in incompletely obliterated cerebral AVM is an effective treatment option with a high rate of treatment response and an acceptable risk for side effects. Marginal doses above 15Gy might further improve the rate of complete obliterations. |
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| DOI: | doi:10.1016/j.radonc.2011.01.002 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.radonc.2011.01.002 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0167814011000168 |
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| | DOI: https://doi.org/10.1016/j.radonc.2011.01.002 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Arteriovenous malformation |
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| | AVM |
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| | Incomplete obliteration |
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| | Radiosurgery |
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| | Radiotherapy |
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| | Reirradiation |
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| K10plus-PPN: | 1817352148 |
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| Verknüpfungen: | → Zeitschrift |
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Repeated linac-based radiosurgery in high-grade cerebral arteriovenous-malformations (AVM) Spetzler-Martin grade III to IV previously treated with radiosurgery / Hauswald, Henrik [VerfasserIn]; [February 2011] (Online-Ressource)
