Global and regional myocardial function quantification in takotsubo cardiomyopathy in comparison to acute anterior myocardial infarction using two-dimensional (2D) strain echocardiography

• Verfasst von: Heggemann, Felix [VerfasserIn]
• Verfasst von: Hamm, Karsten [VerfasserIn]
• Verfasst von: Kälsch, Thorsten [VerfasserIn]
• Verfasst von: Süselbeck, Tim [VerfasserIn]
• Verfasst von: Papavassiliu, Theano [VerfasserIn]
• Verfasst von: Borggrefe, Martin [VerfasserIn]
• Verfasst von: Haghi, Dariusch [VerfasserIn]
• Titel: Global and regional myocardial function quantification in takotsubo cardiomyopathy in comparison to acute anterior myocardial infarction using two-dimensional (2D) strain echocardiography
• Verf.angabe: Felix Heggemann, Karsten Hamm, Thorsten Kaelsch, Tim Sueselbeck, Theano Papavassiliu, Martin Borggrefe, and Dariusch Haghi (First Medical Department, University Medical Centre Mannheim)
• E-Jahr: 2011
• Jahr: [August 2011]
• Umfang: 5 S.
• Fussnoten: First published: 04 May 2011 ; Gesehen am 28.09.2022
• Titel Quelle: Enthalten in: Echocardiography
• Ort Quelle: Armonk, NY : Futura, 1984
• Jahr Quelle: 2011
• Band/Heft Quelle: 28(2011), 7, Seite 715-719
• ISSN Quelle: 1540-8175
• DOI: doi:10.1111/j.1540-8175.2011.01430.x
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: cardiomyopathy
• Sach-SW: echocardiography
• Sach-SW: left ventricular systolic function
• Sach-SW: myocardial infarction
• Sach-SW: strain
• K10plus-PPN: 1817721356

Abstract

Aims: This study sought to compare global and regional myocardial function in Takotsubo cardiomyopathy (TC) to that in acute anterior myocardial infarction (AMI) using 2D strain imaging. Methods: Twelve consecutive patients with TC (ten women, two men) and 12 patients with AMI (four women, eight men) underwent 2D echocardiography at initial presentation. 2D strain images were analyzed to measure longitudinal and radial strain. Global strain was calculated as the average longitudinal strain of the segments of two-, three-, and four-chamber views. Biplane ejection fraction was assessed using Simpson's biplane method. Results: Significant differences in radial strain (TC vs. AMI) were found in lateral (13.5 ± 10.1% vs. 25.1 ± 11.2%, P = 0.035), posterior (15.2 ± 14.5% vs. 51.4 ± 14.2%, P < 0.001), and inferior (17.9 ± 15.5% vs. 49.4 ± 16.9%, P = 0.002) segments. Longitudinal strain was significantly lower in TC in basal-inferior (−15.8 ± 9.2% vs. −22.7 ± 3.8%, P = 0.037), midinferior (−8.3 ± 9.2% vs. −16.8 ± 3.0%, P = 0.004), basal-posterior (−12.2 ± 9.4% vs. −21.6 ± 4.4%, P = 0.016), midposterior (−4.4 ± 8.0% vs. −15.4 ± 3.5%, P = 0.002), apical-posterior (2.3 ± 6.7% vs. −6.4 ± 10.1%, P = 0.023), and midlateral (−3.4 ± 6.9% vs. −9.5 ± 5.8%, P = 0.028) segments. Global strain and ejection fraction were significantly higher in patients with AMI (−3.5 ± 8.2% vs. −10.3 ± 8.4%, P < 0.001 and 37 ± 11% vs. 46 ± 11%, P = 0.045). Conclusion: In TC, strain was reduced around the entire mid left-ventricular circumference, whereas in AMI it was predominantly reduced in the anterior and anteroseptal wall. These observed differences confirm the notion that TC affects myocardium beyond the territory of a single coronary artery. They may allow noninvasive distinction between both entities. (Echocardiography 2011;28:715-719)