| |  Online-Ressource |
|---|
| Verfasst von: | Gräfe, David [VerfasserIn]  |
|---|
| | Gernhardt, Marvin [VerfasserIn] |
|---|
| | Ren, Jiongyu [VerfasserIn] |
|---|
| | Blasco, Eva [VerfasserIn] |
|---|
| | Wegener, Martin [VerfasserIn] |
|---|
| | Woodruff, Maria Ann [VerfasserIn] |
|---|
| | Barner-Kowollik, Christopher [VerfasserIn] |
|---|
| Titel: | Enzyme-degradable 3D multi-material microstructures |
|---|
| Verf.angabe: | David Gräfe, Marvin Gernhardt, Jiongyu Ren, Eva Blasco, Martin Wegener, Maria Ann Woodruff, and Christopher Barner-Kowollik |
|---|
| Jahr: | 2021 |
|---|
| Umfang: | 8 S. |
|---|
| Fussnoten: | Published online: October 7, 2020 ; Gesehen am 12.10.2022 |
|---|
| Titel Quelle: | Enthalten in: Advanced functional materials |
|---|
| Ort Quelle: | Weinheim : Wiley-VCH, 2001 |
|---|
| Jahr Quelle: | 2021 |
|---|
| Band/Heft Quelle: | 31(2021), 3, Artikel-ID 2006998, Seite 1-8 |
|---|
| ISSN Quelle: | 1616-3028 |
|---|
| Abstract: | There exists a growing need for smart materials suitable for use in biomedical applications. Herein, a photoresist that can be used to fabricate a biocompatible material entirely degradable by the enzyme chymotrypsin is introduced. The photoresist is based on a crosslinker with a tyramine moiety that is recognized and cleaved by the enzyme chymotrypsin. Macroscopic films as well as microstructures are fabricated via the use of direct laser writing. Multi-material boxing ring microstructures are generated and selectively degraded by the enzyme. Cell biocompatibility studies indicate that cells are able to attach and proliferate over one week on the material. A photoresist that is biocompatible and can be entirely removed by a biocompatible stimulus such as an enzyme can potentially be used as an easily removed tissue engineering scaffold and is especially promising for basic cell biology research. |
|---|
| DOI: | doi:10.1002/adfm.202006998 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1002/adfm.202006998 |
|---|
| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202006998 |
|---|
| | DOI: https://doi.org/10.1002/adfm.202006998 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | biocompatibility |
|---|
| | direct laser writing |
|---|
| | enzyme-degradability |
|---|
| | microstructures |
|---|
| K10plus-PPN: | 1818807246 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Enzyme-degradable 3D multi-material microstructures / Gräfe, David [VerfasserIn]; 2021 (Online-Ressource)
