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| Verfasst von: | Sikkes, Sietske [VerfasserIn]  |
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| | Visser, Pieter Jelle [VerfasserIn] |
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| | Knol, Dirk L. [VerfasserIn] |
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| | de Lange-de Klerk, Elly S. M. [VerfasserIn] |
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| | Tsolaki, Magda [VerfasserIn] |
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| | Frisoni, Giovani B. [VerfasserIn] |
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| | Nobili, Flavio [VerfasserIn] |
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| | Spiru, Luiza [VerfasserIn] |
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| | Rigaud, Anne Sophie [VerfasserIn] |
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| | Frölich, Lutz [VerfasserIn] |
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| | Rikkert, Marcel Olde [VerfasserIn] |
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| | Soininen, Hilkka [VerfasserIn] |
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| | Touchon, Jacques [VerfasserIn] |
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| | Wilcock, Gordon [VerfasserIn] |
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| | Boada, Mercè [VerfasserIn] |
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| | Hampel, Harald [VerfasserIn] |
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| | Bullock, Roger [VerfasserIn] |
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| | Vellas, Bruno [VerfasserIn] |
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| | Pijnenburg, Yolande A.L. [VerfasserIn] |
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| | Scheltens, Philip [VerfasserIn] |
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| | Verhey, Frans R. [VerfasserIn] |
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| | Uitdehaag, Bernard M.J. [VerfasserIn] |
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| Titel: | Do instrumental activities of daily living predict Dementia at 1- and 2-year follow-up? |
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| Titelzusatz: | findings from the development of screening guidelines and diagnostic criteria for predementia Alzheimer's disease study |
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| Verf.angabe: | Sietske A.M. Sikkes, Pieter Jelle Visser, Dirk L. Knol, Elly S.M. de Lange-de Klerk, Magda Tsolaki, Giovani B. Frisoni, Flavio Nobili, Luiza Spiru, Anne Sophie Rigaud, Lutz Frölich, Marcel Olde Rikkert, Hilkka Soininen, Jacques Touchon, Gordon Wilcock, Mercè Boada, Harald Hampel, Roger Bullock, Bruno Vellas, Yolande A.L. Pijnenburg, Philip Scheltens, Frans R. Verhey, and Bernard M.J. Uitdehaag |
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| E-Jahr: | 2011 |
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| Jahr: | 20 December 2011 |
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| Umfang: | 9 S. |
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| Fussnoten: | Gesehen am 13.10.2022 |
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| Titel Quelle: | Enthalten in: American Geriatrics SocietyJournal of the American Geriatrics Society |
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| Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1953 |
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| Jahr Quelle: | 2011 |
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| Band/Heft Quelle: | 59(2011), 12, Seite 2273-2281 |
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| ISSN Quelle: | 1532-5415 |
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| Abstract: | Objectives To investigate whether problems in instrumental activities of daily living (IADL) can add to conventionally used clinical measurements in helping to predict a diagnosis of dementia at 1- and 2-year follow-up. Design Multicenter prospective cohort study. Setting Memory clinics in Europe. Participants Individuals aged 55 and older without dementia. Measurements IADLs were measured using pooled activities from five informant-based questionnaires. Structural equation modeling (SEM) was used to investigate the relation between IADLs and dementia. Age, sex, education, depression, and cognitive measures (Mini-Mental State Examination and verbal memory) were included in the model. Results Five hundred thirty-one participants had baseline and 1-year follow-up assessments; 69 (13.0%) of these had developed dementia at 1-year follow-up. At 2-year follow-up, 481 participants were seen, of whom 100 (20.8%) had developed dementia. Participants with IADL disabilities at baseline had a higher conversion rate (24.4%) than participants without IADL disabilities (16.7%) (chi-square = 4.28, degrees of freedom = 1, P = .04). SEM showed that IADL disability could help predict dementia in addition to the measured variables at 1-year follow-up (odds ratio (OR) = 2.20, 95% confidence interval (CI) = 1.51-3.13) and 2-year follow-up (OR = 2.11, 95% CI = 1.33-3.33). Conclusion IADL disability is a useful addition to the diagnostic process in a memory clinic setting, indicating who is at higher risk of developing dementia at 1- and 2-year follow-up. |
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| DOI: | doi:10.1111/j.1532-5415.2011.03732.x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1111/j.1532-5415.2011.03732.x |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1532-5415.2011.03732.x |
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| | DOI: https://doi.org/10.1111/j.1532-5415.2011.03732.x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | activities of daily living |
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| | Alzheimer's disease |
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| | everyday functioning |
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| | memory |
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| | mild cognitive impairment |
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| | structural equation modeling |
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| K10plus-PPN: | 1818893169 |
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| Verknüpfungen: | → Zeitschrift |
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Do instrumental activities of daily living predict Dementia at 1- and 2-year follow-up? / Sikkes, Sietske [VerfasserIn]; 20 December 2011 (Online-Ressource)
