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| Verfasst von: | Strobel, Catrin [VerfasserIn]  |
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| | Kadow-Romacker, Anke [VerfasserIn] |
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| | Witascheck, Tom [VerfasserIn] |
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| | Schmidmaier, Gerhard [VerfasserIn] |
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| | Wildemann, Britt [VerfasserIn] |
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| Titel: | Evaluation of process parameter of an automated dip-coating |
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| Verf.angabe: | Catrin Strobel, Anke Kadow-Romacker, Tom Witascheck, Gerhard Schmidmaier, Britt Wildemann |
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| E-Jahr: | 2011 |
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| Jahr: | 5 August 2011 |
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| Umfang: | 4 S. |
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| Fussnoten: | Gesehen am 24.10.2022 |
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| Titel Quelle: | Enthalten in: Materials letters |
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| Ort Quelle: | New York, NY [u.a.] : Elsevier, 1982 |
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| Jahr Quelle: | 2011 |
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| Band/Heft Quelle: | 65(2011), 23, Seite 3621-3624 |
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| ISSN Quelle: | 1873-4979 |
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| Abstract: | Dip coating is a common technique for the optimization of metallic implants, whereas several steps during the procedure influence the coating. This study aims in the development of a coating apparatus and the evaluation of critical steps, such as mixing, immersion, retention and withdrawal velocity during the procedure. In addition the influence of the polymer solution viscosity, poly(d,l-lactide) dissolved in ethyl acetate, was analyzed. As a therapeutic drug, gentamicin was incorporated and the amount in the different coatings quantified. With increased withdrawal velocity and viscosity the thickness of the coating layer increased. This was accompanied by an increase in incorporated drug. The mixing, immersion and retention time had almost no effect. The viscosity of the polymer solution and the withdrawal velocity can therefore be used to modify bioactive coatings for optimized local drug loading. |
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| DOI: | doi:10.1016/j.matlet.2011.07.102 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.matlet.2011.07.102 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0167577X11008822 |
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| | DOI: https://doi.org/10.1016/j.matlet.2011.07.102 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Automatization |
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| | Dip coating |
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| | Drug load |
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| | poly(-lactide) |
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| | Viscosity |
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| | Withdrawal velocity |
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| K10plus-PPN: | 1819789802 |
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| Verknüpfungen: | → Zeitschrift |
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Evaluation of process parameter of an automated dip-coating / Strobel, Catrin [VerfasserIn]; 5 August 2011 (Online-Ressource)
