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Verfasst von:Teichert, Katrin [VerfasserIn]   i
 Süss, P. [VerfasserIn]   i
 Serna, J. I. [VerfasserIn]   i
 Monz, M. [VerfasserIn]   i
 Küfer, K. H. [VerfasserIn]   i
 Thieke, Christian [VerfasserIn]   i
Titel:Comparative analysis of Pareto surfaces in multi-criteria IMRT planning
Verf.angabe:K Teichert, P Süss, JI Serna, M Monz, KH Küfer and C Thieke
E-Jahr:2011
Jahr:25 May 2011
Umfang:16 S.
Fussnoten:Gesehen am 26.10.2022
Titel Quelle:Enthalten in: Physics in medicine and biology
Ort Quelle:Bristol : IOP Publ., 1956
Jahr Quelle:2011
Band/Heft Quelle:56(2011), 12, Seite 3669-3684
ISSN Quelle:1361-6560
Abstract:In the multi-criteria optimization approach to IMRT planning, a given dose distribution is evaluated by a number of convex objective functions that measure tumor coverage and sparing of the different organs at risk. Within this context optimizing the intensity profiles for any fixed set of beams yields a convex Pareto set in the objective space. However, if the number of beam directions and irradiation angles are included as free parameters in the formulation of the optimization problem, the resulting Pareto set becomes more intricate. In this work, a method is presented that allows for the comparison of two convex Pareto sets emerging from two distinct beam configuration choices. For the two competing beam settings, the non-dominated and the dominated points of the corresponding Pareto sets are identified and the distance between the two sets in the objective space is calculated and subsequently plotted. The obtained information enables the planner to decide if, for a given compromise, the current beam setup is optimal. He may then re-adjust his choice accordingly during navigation. The method is applied to an artificial case and two clinical head neck cases. In all cases no configuration is dominating its competitor over the whole Pareto set. For example, in one of the head neck cases a seven-beam configuration turns out to be superior to a nine-beam configuration if the highest priority is the sparing of the spinal cord. The presented method of comparing Pareto sets is not restricted to comparing different beam angle configurations, but will allow for more comprehensive comparisons of competing treatment techniques (e.g. photons versus protons) than with the classical method of comparing single treatment plans.
DOI:doi:10.1088/0031-9155/56/12/014
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1088/0031-9155/56/12/014
 Volltext: https://dx.doi.org/10.1088/0031-9155/56/12/014
 DOI: https://doi.org/10.1088/0031-9155/56/12/014
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1820073882
Verknüpfungen:→ Zeitschrift

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