High-resolution phase-contrast MRI of aortic and pulmonary blood flow during rest and physical exercise using a MRI compatible bicycle ergometer

• Verfasst von: Weber, Tim [VerfasserIn]
• Verfasst von: Tengg-Kobligk, Hendrik von [VerfasserIn]
• Verfasst von: Kopp-Schneider, Annette [VerfasserIn]
• Verfasst von: Ley-Zaporozhan, Julia [VerfasserIn]
• Verfasst von: Kauczor, Hans-Ulrich [VerfasserIn]
• Verfasst von: Ley, Sebastian [VerfasserIn]
• Titel: High-resolution phase-contrast MRI of aortic and pulmonary blood flow during rest and physical exercise using a MRI compatible bicycle ergometer
• Verf.angabe: Tim Frederik Weber, Hendrik von Tengg-Kobligk, Annette Kopp-Schneider, Julia Ley-Zaporozhan, Hans-Ulrich Kauczor, Sebastian Ley
• Jahr: 2011
• Umfang: 6 S.
• Fussnoten: Online verfügbar 31 July 2010 ; Gesehen am 11.11.2022
• Titel Quelle: Enthalten in: European journal of radiology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1990
• Jahr Quelle: 2011
• Band/Heft Quelle: 80(2011), 1 vom: Okt., Seite 103-108
• ISSN Quelle: 1872-7727
• DOI: doi:10.1016/j.ejrad.2010.06.045
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Aorta
• Sach-SW: Blood flow quantification
• Sach-SW: Ergometry
• Sach-SW: Phase-contrast magnetic resonance imaging
• Sach-SW: Pulmonary artery
• K10plus-PPN: 1822075319

Abstract

Purpose - To establish high-resolution phase-contrast magnetic resonance imaging (PC-MRI) using a MRI compatible bicycle ergometer to quantify aortic and pulmonary blood flow during resting conditions and exercise. - Materials and methods - In 20 healthy volunteers (mean age, 26.8±5.0 years) high-resolution PC-MRI (mean temporal resolution, 7.4±3.2ms) was performed in the ascending aorta (AA) and main pulmonary artery (PA) during physical rest and three exercise stages: stage 1, no-load operation; stage 2, heart rate increase 40% compared to rest; stage 3, heart rate increase 80% compared to rest. Flow quantification in AA and PA included flow volume (FV), average velocity (AV), peak velocity (PV) and time to PV (TP). - Results - In stage 1 only TP demonstrated a significant change. With progression to stage 2, all parameters altered significantly. Flow measurements during stage 3 evidenced further alterations only of AV and TP regarding both AA and PA. The deviation of the heart rate from the desired target value was significantly higher for stage 3 compared to stage 2, and 15% of the subjects did not reach the desired target heart rate of stage 3 at all. - Conclusion - Flow quantification by high-resolution PC-MRI during exercise using a MRI compatible bicycle ergometer is feasible. Medium exercise stages are necessary and sufficient to demonstrate flow alterations in healthy volunteers. PC-MRI ergometry may give insights into aberrant hemodynamic conditions in patients with cardiovascular and pulmonary disease.