Long-term neurocognitive function after whole-brain radiotherapy in patients with melanoma brain metastases in the era of immunotherapy

• Verfasst von: Salzmann, Martin [VerfasserIn]
• Verfasst von: Hess, Klaus [VerfasserIn]
• Verfasst von: Uzun-Lang, Kristin [VerfasserIn]
• Verfasst von: Enk, Alexander [VerfasserIn]
• Verfasst von: Jordan, Berit [VerfasserIn]
• Verfasst von: Hassel, Jessica C. [VerfasserIn]
• Titel: Long-term neurocognitive function after whole-brain radiotherapy in patients with melanoma brain metastases in the era of immunotherapy
• Verf.angabe: Martin Salzmann, Klaus Hess, Kristin Lang, Alexander H. Enk, Berit Jordan, Jessica C. Hassel
• E-Jahr: 2022
• Jahr: October 2022
• Umfang: 8 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 17.11.2022
• Titel Quelle: Enthalten in: Strahlentherapie und Onkologie
• Ort Quelle: Berlin : Springer Medizin, 1997
• Jahr Quelle: 2022
• Band/Heft Quelle: 198(2022), 10, Seite 884-891
• ISSN Quelle: 1439-099X
• DOI: doi:10.1007/s00066-022-01950-1
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Brain metastases
• Sach-SW: Cognitive functioning
• Sach-SW: Melanoma
• Sach-SW: Neurocognition
• Sach-SW: Whole-brain radiotherapy
• K10plus-PPN: 1822819741
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext

Abstract

Whole-brain radiotherapy (WBRT) used to be standard of care for patients suffering from melanoma brain metastases (MBM) and may still be applicable in selected cases. Deterioration of neurocognitive function (NCF) is commonly seen during and after WBRT. Knowledge on long-term effects in melanoma patients is limited due to short survival rates. With the introduction of immune checkpoint inhibitors, patients may experience ongoing disease control, emphasizing the need for paying more attention to potential long-term adverse effects.