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Verfasst von:Wu, Jau-Ching [VerfasserIn]   i
 Liu, Laura [VerfasserIn]   i
 Chen, Yu-Chun [VerfasserIn]   i
 Huang, Wen-Cheng [VerfasserIn]   i
 Chen, Tzeng-Ji [VerfasserIn]   i
 Cheng, Henrich [VerfasserIn]   i
Titel:Ossification of the posterior longitudinal ligament in the cervical spine
Titelzusatz:an 11-year comprehensive national epidemiology study
Verf.angabe:Jau-Ching Wu, Laura Liu, Yu-Chun Chen, Wen-Cheng Huang, Tzeng-Ji Chen, and Henrich Cheng
E-Jahr:2011
Jahr:March 2011
Umfang:6 S.
Fussnoten:Gesehen am 05.12.2022
Titel Quelle:Enthalten in: Neurosurgical focus
Ort Quelle:Charlottesville, Va. : American Assoc. of Neurological Surgeons, 1996
Jahr Quelle:2011
Band/Heft Quelle:30(2011), 3, Artikel-ID E5, Seite 1-6
ISSN Quelle:1092-0684
Abstract:Object This study aimed to calculate the incidence and prevalence of ossification of the posterior longitudinal ligament (OPLL) in the cervical spine with its comorbid disability. Methods Using an 11-year nationwide database in Taiwan (National Health Insurance Research Database), this retrospective study cohort analyzed the incidences of cervical OPLL causing hospitalization. All patients admitted for the diagnosis of OPLL, regardless of surgery, were identified. Age- and sex-specific incidences, Poisson regression, and multivariate logistic regression analysis were conducted. Results Between 1997 and 2007 covering 241,800,725.8 person-years, 1651 patients were admitted for OPLL. The overall incidence of OPLL-related admission was 6.1 per 1 million person-years. Specifically, male sex and older age were associated with higher OPLL incidences (both p < 0.001). Among the 1651 OPLL patients, 542 (32.8%) received conservative management, 612 (37.1%) had anterior only surgery, 353 (21.4%) had posterior only surgery, and 144 (8.7%) had anterior and posterior surgery. Eighty-five patients were moderately to severely disabled (5.2% cumulative incidence rate). The incidences of disability varied by age, in a decreasing trend, except for the 60- to 69-year-old age group (p = 0.05). Patients who received posterior-only surgery were more likely to have disability. Conclusions In a large cohort of the Chinese population, the incidence of cervical OPLL-related admission is 6.1 per 1 million person-years, and the prevalence rate is 7.7 per 100,000 person-years. Higher incidences are observed in elderly and male patients, which implies the disease's degenerative nature. After adjustments for demographics, the incidences and trends of OPLL-related comorbid disability are associated with age and surgical approaches.
DOI:doi:10.3171/2010.12.FOCUS10268
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.3171/2010.12.FOCUS10268
 Volltext: https://thejns.org/focus/view/journals/neurosurg-focus/30/3/2010.12.focus10268.xml
 DOI: https://doi.org/10.3171/2010.12.FOCUS10268
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1824429223
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