| Online-Ressource |
Verfasst von: | Schuth, Sebastian [VerfasserIn]  |
| Le Blanc, Solange [VerfasserIn]  |
| Krieger, Teresa G. [VerfasserIn]  |
| Jabs, Julia [VerfasserIn]  |
| Schenk, Miriam [VerfasserIn]  |
| Giese, Nathalia [VerfasserIn]  |
| Büchler, Markus W. [VerfasserIn]  |
| Eils, Roland [VerfasserIn]  |
| Conrad, Christian [VerfasserIn]  |
| Strobel, Oliver [VerfasserIn]  |
Titel: | Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system |
Verf.angabe: | Sebastian Schuth, Solange Le Blanc, Teresa G. Krieger, Julia Jabs, Miriam Schenk, Nathalia A. Giese, Markus W. Büchler, Roland Eils, Christian Conrad and Oliver Strobel |
E-Jahr: | 2022 |
Jahr: | 22 October 2022 |
Umfang: | 14 S. |
Fussnoten: | Gesehen am 10.01.2023 |
Titel Quelle: | Enthalten in: Journal of experimental & clinical cancer research |
Ort Quelle: | Berlin : Springer, 2008 |
Jahr Quelle: | 2022 |
Band/Heft Quelle: | 41(2022), Artikel-ID 312, Seite 1-14 |
ISSN Quelle: | 1756-9966 |
Abstract: | Cancer-associated fibroblasts (CAFs) are considered to play a fundamental role in pancreatic ductal adenocarcinoma (PDAC) progression and chemoresistance. Patient-derived organoids have demonstrated great potential as tumor avatars for drug response prediction in PDAC, yet they disregard the influence of stromal components on chemosensitivity. |
DOI: | doi:10.1186/s13046-022-02519-7 |
URL: | kostenfrei: Volltext: https://doi.org/10.1186/s13046-022-02519-7 |
| kostenfrei: Volltext: https://jeccr.biomedcentral.com/articles/10.1186/s13046-022-02519-7 |
| DOI: https://doi.org/10.1186/s13046-022-02519-7 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Cancer-associated fibroblasts |
| Drug screening |
| Pancreatic cancer |
| Patient-derived organoids |
| Personalized oncology |
K10plus-PPN: | 1830636162 |
Verknüpfungen: | → Zeitschrift |
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Lokale URL UB: | Zum Volltext |
Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system / Schuth, Sebastian [VerfasserIn]; 22 October 2022 (Online-Ressource)