Diagnostic accuracy comparing OPT and CBCT in the detection of non-vital bone changes before tooth extractions in patients with antiresorptive intake

• Verfasst von: Ristow, Oliver [VerfasserIn]
• Verfasst von: Schnug, Gregor [VerfasserIn]
• Verfasst von: Smielowski, Maximilian [VerfasserIn]
• Verfasst von: Moratin, Julius [VerfasserIn]
• Verfasst von: Pilz, Maximilian [VerfasserIn]
• Verfasst von: Engel, Michael [VerfasserIn]
• Verfasst von: Freudlsperger, Christian [VerfasserIn]
• Verfasst von: Hoffmann, Jürgen [VerfasserIn]
• Verfasst von: Rückschloß, Thomas [VerfasserIn]
• Titel: Diagnostic accuracy comparing OPT and CBCT in the detection of non-vital bone changes before tooth extractions in patients with antiresorptive intake
• Verf.angabe: Oliver Ristow, Gregor Schnug, Maximilian Smielowksi, Julius Moratin, Maximilian Pilz, Michael Engel, Christian Freudlsperger, Jürgen Hoffmann, Thomas Rückschloß
• Jahr: 2023
• Umfang: 11 S.
• Fussnoten: Gesehen am 11.01.2023
• Titel Quelle: Enthalten in: Oral diseases
• Ort Quelle: Oxford [u.a.] : Wiley-Blackwell, 1995
• Jahr Quelle: 2023
• Band/Heft Quelle: 29(2023), 3, Seite 1039-1049
• ISSN Quelle: 1601-0825
• DOI: doi:10.1111/odi.14048
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: BRONJ
• Sach-SW: imaging
• Sach-SW: MRONJ
• Sach-SW: prevention
• Sach-SW: radiological signs
• Sach-SW: stage
• Sach-SW: tooth extraction
• K10plus-PPN: 1830757636
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext

Abstract

Objectives To compare the diagnostic accuracy in detecting early non-vital bone changes between orthopantomography (OPT) and cone-beam computed tomography (CBCT) in correlation with histopathological findings before tooth extractions in patients with antiresorptive (AR) intake. Subjects Patients with an indication tooth extraction who had received OPT and CBCT preoperatively while or after undergoing AR treatment were prospectively enrolled over a 24-month period in the progesterone in spontaneous miscarriage (PRISM) trial. Imaging studies were randomly analyzed by three examiners for early non-vital bone changes using specific predefined characteristics and a 5-level scale (1 definite absence of criteria to 5 definite presence of criteria). Sensitivity and specificity values were calculated in correlation with the histopathologically evaluated bone samples at the time point of tooth extraction. Results One hundred thirty patients with 237 treated extraction sites met the inclusion criteria. For all images evaluated by all examiners, CBCT (430/492; 87.4%; receiver operating characteristic [ROC]: area under the curve [AUC] = 0.88; p < 0.001) was more likely to detect histopathologically confirmed non-vital bone than the OPT (132/492; 26.8%; ROC: AUC = 0.562; p = 0.115). Conclusions In the detection of non-vital bone changes, CBCT is superior to OPT in both sensitivity and specificity. Specific imaging characteristics allow for the prediction of early non-vital bone changes already at the time before tooth extractions.