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| Verfasst von: | Pütz, Volker [VerfasserIn]  |
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| | Khomenko, Andrei [VerfasserIn] |
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| | Hill, Michael D. [VerfasserIn] |
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| | Dzialowski, Imanuel [VerfasserIn] |
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| | Michel, Patrik [VerfasserIn] |
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| | Weimar, Christian [VerfasserIn] |
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| | Wijman, Christine A. C. [VerfasserIn] |
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| | Mattle, Heinrich P. [VerfasserIn] |
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| | Engelter, Stefan T. [VerfasserIn] |
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| | Muir, Keith W. [VerfasserIn] |
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| | Pfefferkorn, Thomas [VerfasserIn] |
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| | Tanne, David [VerfasserIn] |
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| | Szabo, Kristina [VerfasserIn] |
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| | Kappelle, L. Jaap [VerfasserIn] |
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| | Algra, Ale [VerfasserIn] |
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| | von Kummer, Ruediger [VerfasserIn] |
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| | Demchuk, Andrew M. [VerfasserIn] |
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| | Schonewille, Wouter J. [VerfasserIn] |
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| Titel: | Extent of hypoattenuation on CT angiography source images in basilar artery occlusion |
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| Titelzusatz: | prognostic value in the Basilar Artery International Cooperation Study |
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| Verf.angabe: | Volker Puetz, MD, Andrei Khomenko, MD, Michael D. Hill, MD, Imanuel Dzialowski, MD, Patrik Michel, MD, Christian Weimar, MD, Christine A.C. Wijman, MD, Heinrich P. Mattle, MD, Stefan T. Engelter, MD, Keith W. Muir, MD, Thomas Pfefferkorn, MD, David Tanne, MD,Kristina Szabo, MD, L. Jaap Kappelle, MD, Ale Algra, MD, Ruediger von Kummer, MD, Andrew M. Demchuk, MD, Wouter J. Schonewille, MD, on behalf of the Basilar Artery International Cooperation Study (BASICS) Group |
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| E-Jahr: | 2011 |
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| Jahr: | 29 September 2011 |
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| Umfang: | 6 S. |
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| Fussnoten: | Gesehen am 19.01.2023 |
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| Titel Quelle: | Enthalten in: Stroke |
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| Ort Quelle: | New York, NY : Association, 1970 |
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| Jahr Quelle: | 2011 |
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| Band/Heft Quelle: | 42(2011), 12, Seite 3454-3459 |
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| ISSN Quelle: | 1524-4628 |
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| Abstract: | BACKGROUND AND PURPOSE: The posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) quantifies the extent of early ischemic changes in the posterior circulation with a 10-point grading system. We hypothesized that pc-ASPECTS applied to CT angiography source images predicts functional outcome of patients in the Basilar Artery International Cooperation Study (BASICS). - METHODS: BASICS was a prospective, observational registry of consecutive patients with acute symptomatic basilar artery occlusion. Functional outcome was assessed at 1 month. We applied pc-ASPECTS to CT angiography source images of patients with CT angiography for confirmation of basilar artery occlusion. We calculated unadjusted and adjusted risk ratios (RRs) of pc-ASPECTS dichotomized at ≥8 versus <8. Primary outcome measure was favorable outcome (modified Rankin Scale scores 0-3). Secondary outcome measures were mortality and functional independence (modified Rankin Scale scores 0-2). - RESULTS: Of 158 patients included, 78 patients had a CT angiography source images pc-ASPECTS≥8. Patients with a pc-ASPECTS≥8 more often had a favorable outcome than patients with a pc-ASPECTS<8 (crude RR, 1.7; 95% CI, 0.98-3.0). After adjustment for age, baseline National Institutes of Health Stroke Scale score, and thrombolysis, pc-ASPECTS≥8 was not related to favorable outcome (RR, 1.3; 95% CI, 0.8-2.2), but it was related to reduced mortality (RR, 0.7; 95% CI, 0.5-0.98) and functional independence (RR, 2.0; 95% CI, 1.1-3.8). In post hoc analysis, pc-ASPECTS dichotomized at ≥6 versus <6 predicted a favorable outcome (adjusted RR, 3.1; 95% CI, 1.2-7.5). - CONCLUSIONS: pc-ASPECTS on CT angiography source images independently predicted death and functional independence at 1 month in the CT angiography subgroup of patients in the BASICS registry. |
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| DOI: | doi:10.1161/STROKEAHA.111.622175 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1161/STROKEAHA.111.622175 |
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| | DOI: https://doi.org/10.1161/STROKEAHA.111.622175 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Aged |
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| | Aged, 80 and over |
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| | Basilar Artery |
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| | Cerebral Angiography |
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| | Female |
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| | Humans |
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| | Male |
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| | Middle Aged |
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| | Predictive Value of Tests |
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| | Prognosis |
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| | Prospective Studies |
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| | Radiographic Image Interpretation, Computer-Assisted |
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| | Registries |
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| | Risk Factors |
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| | Tomography, X-Ray Computed |
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| | Vertebrobasilar Insufficiency |
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| K10plus-PPN: | 1831529734 |
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| Verknüpfungen: | → Zeitschrift |
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Extent of hypoattenuation on CT angiography source images in basilar artery occlusion / Pütz, Volker [VerfasserIn]; 29 September 2011 (Online-Ressource)
