| Online-Ressource |
Verfasst von: | Hein, Selina [VerfasserIn]  |
| Furkel, Jennifer [VerfasserIn]  |
| Knoll, Maximilian [VerfasserIn]  |
| Siepen, Fabian aus dem [VerfasserIn]  |
| Schönland, Stefan [VerfasserIn]  |
| Hegenbart, Ute [VerfasserIn]  |
| Katus, Hugo [VerfasserIn]  |
| Kristen, Arnt [VerfasserIn]  |
| Konstandin, Mathias [VerfasserIn]  |
Titel: | Impaired in vitro growth response of plasma-treated cardiomyocytes predicts poor outcome in patients with transthyretin amyloidosis |
Verf.angabe: | Selina Hein, Jennifer Furkel, Maximilian Knoll, Fabian aus dem Siepen, Stefan Schönland, Ute Hegenbart, Hugo A. Katus, Arnt V. Kristen, Mathias H. Konstandin |
E-Jahr: | 2021 |
Jahr: | 22 January 2021 |
Umfang: | 12 S. |
Fussnoten: | Gesehen am 26.01.2023 |
Titel Quelle: | Enthalten in: Clinical research in cardiology |
Ort Quelle: | Berlin : Springer, 2006 |
Jahr Quelle: | 2021 |
Band/Heft Quelle: | 110(2021), 4, Seite 579-590 |
ISSN Quelle: | 1861-0692 |
Abstract: | Direct toxic effects of transthyretin amyloid in patient plasma upon cardiomyocytes are discussed. However, no data regarding the relevance of this putative effect for clinical outcome are available. In this monocentric prospective study, we analyzed cellular hypertrophy after phenylephrine stimulation in vitro in the presence of patient plasma and correlated the cellular growth response with phenotype and prognosis. |
DOI: | doi:10.1007/s00392-020-01801-y |
URL: | kostenfrei: Volltext: https://doi.org/10.1007/s00392-020-01801-y |
| DOI: https://doi.org/10.1007/s00392-020-01801-y |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Amyloidosis |
| Hypertrophy |
| In-vitro assay |
| Transthyretin |
K10plus-PPN: | 1832506282 |
Verknüpfungen: | → Zeitschrift |
|
|
| |
Lokale URL UB: | Zum Volltext |
Impaired in vitro growth response of plasma-treated cardiomyocytes predicts poor outcome in patients with transthyretin amyloidosis / Hein, Selina [VerfasserIn]; 22 January 2021 (Online-Ressource)