Anaesthesia as an influence in tumour progression

• Verfasst von: Poßmann, Jadie [VerfasserIn]
• Verfasst von: Wirsik, Naita Maren [VerfasserIn]
• Verfasst von: Ritter, Alina [VerfasserIn]
• Verfasst von: Schmidt, Thomas [VerfasserIn]
• Verfasst von: Weigand, Markus A. [VerfasserIn]
• Titel: Anaesthesia as an influence in tumour progression
• Verf.angabe: Jadie Plücker, Naita M. Wirsik, Alina S. Ritter, Thomas Schmidt, Markus A. Weigand
• E-Jahr: 2021
• Jahr: 01 February 2021
• Fussnoten: Gesehen am 21.02.2023
• Titel Quelle: Enthalten in: Langenbeck's archives of surgery
• Ort Quelle: Berlin : Springer, 1948
• Jahr Quelle: 2021
• Band/Heft Quelle: 406(2021), 5, Seite 1283-1294
• ISSN Quelle: 1435-2451
• DOI: doi:10.1007/s00423-021-02078-z
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Cancer recurrence
• Sach-SW: General anaesthesia
• Sach-SW: Metastasis
• Sach-SW: Narcotics
• Sach-SW: Opioids
• Sach-SW: Regional anaesthesia
• K10plus-PPN: 1837185549
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext

Abstract

Tumour growth and the formation of metastases are essential elements in the progression of cancer. The centre of treatment is the surgical resection of primary solid tumours. But even if the tumour can be removed without microscopic residual cells, local recurrences and distant metastases occur and determine the patient’s fate. During the operation, tumour cells are shed from the primary tumour and released into the circulation. These circulating tumour cells might play an important role in the formation of new tumour sites. Therefore, a functional innate and adaptive immune system is essential, especially in this perioperative period. Anaesthesia influences consciousness and pain perception and interacts directly with the immune system and tumour cells.