Synergistic effect of cinacalcet and active vitamin D in a dialysis patient with secondary hyperparathyroidism

• Verfasst von: Karger, Christian [VerfasserIn]
• Verfasst von: Schwenger, Vedat [VerfasserIn]
• Verfasst von: Sommerer, Claudia [VerfasserIn]
• Verfasst von: Zeier, Martin [VerfasserIn]
• Titel: Synergistic effect of cinacalcet and active vitamin D in a dialysis patient with secondary hyperparathyroidism
• Verf.angabe: Christian P. Karger, Vedat Schwenger, Claudia Sommerer, Martin Zeier
• E-Jahr: 2010
• Jahr: 25 February 2010
• Umfang: 3 S.
• Fussnoten: Gesehen am 02.03.2023
• Titel Quelle: Enthalten in: Dialysis & transplantation
• Ort Quelle: Hoboken NJ : Wiley, 2006
• Jahr Quelle: 2010
• Band/Heft Quelle: 39(2010), 2 vom: Feb., Seite 69-71
• ISSN Quelle: 1932-6920
• DOI: doi:10.1002/dat.20405
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1837927154

Abstract

While treating a long-term dialysis patient for secondary hyperparathyroidism (SHPT), indications of a synergistic effect between cinacalcet HCl and active vitamin D were observed. After 2.5 years, high initial cinacalcet doses of 180 mg/day could be significantly reduced to only 30 mg/non-dialysis day without losing control over the intact parathyroid hormone. Calcium-phosphorus product improved over time. The combination of cinacalcet and active vitamin D may improve the treatment of SHPT in dialysis patients.