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Verfasst von:Labrosse, Michel [VerfasserIn]   i
 Lobo, Keegan [VerfasserIn]   i
 Beller, Carsten J. [VerfasserIn]   i
Titel:Structural analysis of the natural aortic valve in dynamics
Titelzusatz:from unpressurized to physiologically loaded
Verf.angabe:Michel R. Labrosse, Keegan Lobo, Carsten J. Beller
E-Jahr:2010
Jahr:7 April 2010
Umfang:7 S.
Fussnoten:Gesehen am 09.03.2023
Titel Quelle:Enthalten in: Journal of biomechanics
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 1968
Jahr Quelle:2010
Band/Heft Quelle:43(2010), 10 vom: Apr., Seite 1916-1922
ISSN Quelle:1873-2380
Abstract:A novel finite element model of the natural aortic valve was developed implementing anisotropic hyperelastic material properties for the leaflets and aortic tissues, and starting from the unpressurized geometry. Static pressurization of the aortic root, silicone rubber moulds and published data helped to establish the model parameters, while high-speed video recording of the leaflet motion in a left-heart simulator allowed for comparisons with simulations. The model was discretized with brick elements and loaded with time-varying pressure using an explicit commercial solver. The aortic valve model produced a competent valve whose dynamic behavior (geometric orifice area vs. time) closely matched that observed in the experiment. In both cases, the aortic valve took approximately 30ms to open to an 800mm2 orifice and remained completely or more than half open for almost 200ms, after which it closed within 30-50ms. The highest values of stress were along the leaflet attachment line and near the commissure during diastole. Von Mises stress in the leaflet belly reached 600-750kPa from early to mid-diastole. While the model using the unpressurized geometry as initial configuration was specially designed to satisfy the requirements of continuum mechanics for large deformations of hyperelastic materials, it also clearly demonstrated that dry models can be adequate to analyze valve dynamics. Although improvements are still needed, the advanced modeling and validation techniques used herein contribute toward improved and quantified accuracy over earlier simplified models.
DOI:doi:10.1016/j.jbiomech.2010.03.020
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.jbiomech.2010.03.020
 Volltext: https://www.sciencedirect.com/science/article/pii/S002192901000165X
 DOI: https://doi.org/10.1016/j.jbiomech.2010.03.020
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Aortic valve
 Dynamics
 Finite element analysis
 Orifice area
K10plus-PPN:1838729291
Verknüpfungen:→ Zeitschrift

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