Unusual extramedullary manifestation in multiple myeloma

• Verfasst von: Strauss, Dimitrios [VerfasserIn]
• Verfasst von: Sachpekidis, Christos [VerfasserIn]
• Verfasst von: Dapunt, Ulrike A. [VerfasserIn]
• Verfasst von: Goldschmidt, Hartmut [VerfasserIn]
• Verfasst von: Dimitrakopoulou-Strauss, Antonia [VerfasserIn]
• Titel: Unusual extramedullary manifestation in multiple myeloma
• Titelzusatz: bilateral synchronous testicular infiltration
• Verf.angabe: Dimitrios Strauss, Christos Sachpekidis, Ulrike Dapunt, Hartmut Goldschmidt, Antonia Dimitrakopoulou-Strauss
• E-Jahr: 2023
• Jahr: February 2023
• Umfang: 2 S.
• Fussnoten: Gesehen am 15.03.2023
• Titel Quelle: Enthalten in: Clinical nuclear medicine
• Ort Quelle: Philadelphia, Pa. : Lippincott Williams & Wilkins, 1976
• Jahr Quelle: 2023
• Band/Heft Quelle: 48(2023), 2 vom: Feb., Seite e76-e77
• ISSN Quelle: 1536-0229
• DOI: doi:10.1097/RLU.0000000000004496
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1839268492

Abstract

A 73-year-old man with multiple myeloma (initial diagnosis 21 months earlier) was referred to our center for a whole-body 18F-FDG PET/CT. We detected a bilateral synchronous testicular manifestation, which was confirmed by histopathology after orchiectomy. Besides hypermetabolic lesions in the spine and ribs (most likely old fractures), known osteolysis showed no uptake. Extramedullary manifestation occurs in 13% to 20% of cases, among these 4% demonstrate testicular manifestation, which is associated with poor survival rates. Optimal therapy management is still unclear, due to limited data. To the authors’ knowledge, so far only 3 comparable cases have been described.