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Verfasst von:Şandra-Petrescu, Flavius Ionuţ [VerfasserIn]   i
 Tzatzarakis, Emmanouil [VerfasserIn]   i
 Mansour Basha, Mamdouh [VerfasserIn]   i
 Rückert, Felix [VerfasserIn]   i
 Reißfelder, Christoph [VerfasserIn]   i
 Birgin, Emrullah [VerfasserIn]   i
 Rahbari, Nuh Nabi [VerfasserIn]   i
Titel:Impact of spleen preservation on the incidence of postoperative pancreatic fistula after distal pancreatectomy
Titelzusatz:Is less more?
Verf.angabe:Flavius Șandra-Petrescu, Emmanouil Tzatzarakis, Mamdouh Mansour Basha, Felix Rückert, Christoph Reissfelder, Emrullah Birgin, Nuh N. Rahbari
E-Jahr:2022
Jahr:November 2022
Umfang:7 S.
Fussnoten:Gesehen am 22.03.2023
Titel Quelle:Enthalten in: Pancreatology
Ort Quelle:Amsterdam : Elsevier, 2001
Jahr Quelle:2022
Band/Heft Quelle:22(2022), 7, Seite 1013-1019
ISSN Quelle:1424-3911
Abstract:Background - Postoperative pancreatic fistula (POPF) remains a major complication after distal pancreatectomy (DP) with a significant impact on patients’ quality of life. There is limited evidence that preservation of the spleen reduces the risk of POPF. Therefore, we aimed to investigate the impact of splenectomy on perioperative outcome. - Methods - Data from patients who underwent DP for malignant and benign disease at our institution between 2004 and 2021 were reviewed. Patients were grouped according to spleen preservation (SP-DP) and splenectomy (DPS). Intraoperative parameters and postoperative outcomes were compared between groups. Univariable and multivariable analyses were used to investigate factors that influence the occurrence of clinically relevant (cr)POPF. - Results - A total of 199 patients were included, of whom 61 (30.7%) patients underwent SP-DP. Patients who underwent SP-DP had a significantly lower rate of crPOPF (p = 0.022), shorter hospital stay (p = 0.003), and less readmissions (p = 0.012). On multivariate analysis, obesity (OR 2.88, p = 0.021), benign lesions (OR 2.35, p = 0.018), postoperative acute pancreatitis (OR 2.53, p = 0.028), and splenectomy (OR 2.83, p = 0.011) were independent risk factors associated with the onset of crPOPF. - Discussion - Preservation of the spleen reduces the risk of crPOPF in patients undergoing distal pancreatectomy for benign and malignant disease.
DOI:doi:10.1016/j.pan.2022.07.012
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.pan.2022.07.012
 Volltext: https://www.sciencedirect.com/science/article/pii/S1424390322004677
 DOI: https://doi.org/10.1016/j.pan.2022.07.012
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Benign disease
 Clinically relevant fistula
 Left pancreatectomy
 Malignant disease
 Splenectomy
K10plus-PPN:1839806427
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