A follicular dendritic cell sarcoma of the mediastinum with immature T cells and association with myasthenia gravis

• Verfasst von: Hartert, Marc [VerfasserIn]
• Verfasst von: Ströbel, Philipp [VerfasserIn]
• Verfasst von: Dahm, Manfred [VerfasserIn]
• Verfasst von: Nix, Wilfred [VerfasserIn]
• Verfasst von: Marx, Alexander [VerfasserIn]
• Verfasst von: Vahl, Christian-Friedrich [VerfasserIn]
• Titel: A follicular dendritic cell sarcoma of the mediastinum with immature T cells and association with myasthenia gravis
• Verf.angabe: Marc Hartert, Philipp Ströbel, Manfred Dahm, Wilfred Nix, Alexander Marx, and Christian-Friedrich Vahl
• E-Jahr: 2010
• Jahr: [May 2010]
• Umfang: 4 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 24.03.2023
• Titel Quelle: Enthalten in: The American journal of surgical pathology
• Ort Quelle: Philadelphia, Pa. : Lippincott Williams & Wilkins, 1977
• Jahr Quelle: 2010
• Band/Heft Quelle: 34(2010), 5 vom: Mai, Seite 742-745
• ISSN Quelle: 1532-0979
• DOI: doi:10.1097/PAS.0b013e3181d7a2ee
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1840002115

Abstract

Follicular dendritic cell (FDC) sarcoma is a very rare neoplasm showing morphologic and phenotypic features of FDCs. It occurs primarily in lymph nodes but also in extranodal sites. So far, there have been no reports on FDC sarcoma associated with myasthenia gravis. In the following we will present a case of an FDC tumor of the mediastinum associated with paraneoplastic myasthenia gravis in a 39-year-old man. The tumor contained a major proportion of immature T cells, which may be connected to this patient's very unusual clinical presentation with autoimmune phenomena. Extranodal FDC sarcomas still seem hardly noticed, and their clinical and pathologic characteristics remain to be better defined.