GenomeRNAi

• Verfasst von: Gilsdorf, Moritz [VerfasserIn]
• Verfasst von: Horn, Thomas [VerfasserIn]
• Verfasst von: Arzıman Büyükboduk, Zeynep [VerfasserIn]
• Verfasst von: Pelz, Oliver [VerfasserIn]
• Verfasst von: Kiner, Evgeny [VerfasserIn]
• Verfasst von: Boutros, Michael [VerfasserIn]
• Titel: GenomeRNAi
• Titelzusatz: a database for cell-based RNAi phenotypes$d2009 update
• Verf.angabe: Moritz Gilsdorf, Thomas Horn, Zeynep Arziman, Oliver Pelz, Evgeny Kiner and Michael Boutros
• Jahr: 2010
• Umfang: 5 S.
• Fussnoten: Published online 12 November 2009 ; Gesehen am 24.03.2023
• Titel Quelle: Enthalten in: Nucleic acids research
• Ort Quelle: Oxford : Oxford Univ. Press, 1974
• Jahr Quelle: 2010
• Band/Heft Quelle: 38(2010), suppl_1, Seite D448-D452
• ISSN Quelle: 1362-4962
• DOI: doi:10.1093/nar/gkp1038
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1840008849

Abstract

The GenomeRNAi database (http://www.genomernai.org/) contains phenotypes from published cell-based RNA interference (RNAi) screens in Drosophila and Homo sapiens. The database connects observed phenotypes with annotations of targeted genes and information about the RNAi reagent used for the perturbation experiment. The availability of phenotypes from Drosophila and human screens also allows for phenotype searches across species. Besides reporting quantitative data from genome-scale screens, the new release of GenomeRNAi also enables reporting of data from microscopy experiments and curated phenotypes from published screens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality that are available for the Drosophila and the human genome. The new version also facilitates the integration with other genomic data sets and contains expression profiling (RNA-Seq) data for several cell lines commonly used in RNAi experiments.