| |  Online-Ressource |
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| Verfasst von: | Han, Yi [VerfasserIn]  |
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| | Drobisch, Pascal [VerfasserIn] |
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| | Krüger, Alexander [VerfasserIn] |
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| | William, Doreen [VerfasserIn] |
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| | Grützmann, Konrad [VerfasserIn] |
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| | Böthig, Lukas [VerfasserIn] |
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| | Polster, Heike [VerfasserIn] |
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| | Seifert, Lena [VerfasserIn] |
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| | Seifert, Adrian [VerfasserIn] |
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| | Distler, Marius [VerfasserIn] |
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| | Pecqueux, Mathieu [VerfasserIn] |
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| | Riediger, Carina [VerfasserIn] |
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| | Plodeck, Verena [VerfasserIn] |
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| | Nebelung, Heiner [VerfasserIn] |
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| | Weber, Georg Ferdinand [VerfasserIn] |
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| | Pilarsky, Christian [VerfasserIn] |
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| | Kahlert, Ulf D. [VerfasserIn] |
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| | Hinz, Ulf [VerfasserIn] |
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| | Roth, Susanne [VerfasserIn] |
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| | Hackert, Thilo [VerfasserIn] |
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| | Weitz, Jürgen [VerfasserIn] |
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| | Wong, Fang Cheng [VerfasserIn] |
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| | Kahlert, Christoph [VerfasserIn] |
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| Titel: | Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma |
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| Verf.angabe: | Yi Han, Pascal Drobisch, Alexander Krüger, Doreen William, Konrad Grützmann, Lukas Böthig, Heike Polster, Lena Seifert, Adrian M. Seifert, Marius Distler, Mathieu Pecqueux, Carina Riediger, Verena Plodeck, Heiner Nebelung, Georg F. Weber, Christian Pilarsky, Ulf Kahlert, Ulf Hinz, Susanne Roth, Thilo Hackert, Jürgen Weitz, Fang Cheng Wong and Christoph Kahlert |
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| E-Jahr: | 2023 |
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| Jahr: | 03 February 2023 |
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| Umfang: | 19 S. |
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| Fussnoten: | Gesehen am 24.04.2023 |
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| Titel Quelle: | Enthalten in: Journal of hematology & oncology |
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| Ort Quelle: | London : Biomed Central, 2008 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 16(2023), Artikel-ID 7, Seite 1-19 |
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| ISSN Quelle: | 1756-8722 |
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| Abstract: | The prognosis of pancreatic ductal adenocarcinoma (PDAC) is one of the most dismal of all cancers and the median survival of PDAC patients is only 6-8 months after diagnosis. While decades of research effort have been focused on early diagnosis and understanding of molecular mechanisms, few clinically useful markers have been universally applied. To improve the treatment and management of PDAC, it is equally relevant to identify prognostic factors for optimal therapeutic decision-making and patient survival. Compelling evidence have suggested the potential use of extracellular vesicles (EVs) as non-invasive biomarkers for PDAC. The aim of this study was thus to identify non-invasive plasma-based EV biomarkers for the prediction of PDAC patient survival after surgery. |
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| DOI: | doi:10.1186/s13045-023-01404-w |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1186/s13045-023-01404-w |
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| | DOI: https://doi.org/10.1186/s13045-023-01404-w |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Extracellular vesicles |
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| | mRNA biomarkers |
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| | Pancreatic ductal adenocarcinoma |
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| | Plasma extracellular vesicle |
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| | Prognosis |
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| K10plus-PPN: | 1843409631 |
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| Verknüpfungen: | → Zeitschrift |
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Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma / Han, Yi [VerfasserIn]; 03 February 2023 (Online-Ressource)
