High-resolution 3D unenhanced ECG-gated respiratory-navigated MR angiography of the renal arteries

• Verfasst von: Mohrs, Oliver K. [VerfasserIn]
• Verfasst von: Petersen, Steffen E. [VerfasserIn]
• Verfasst von: Schulze, Thomas [VerfasserIn]
• Verfasst von: Zieschang, Michael [VerfasserIn]
• Verfasst von: Küx, Harald [VerfasserIn]
• Verfasst von: Schmitt, Peter [VerfasserIn]
• Verfasst von: Bergemann, Sabine [VerfasserIn]
• Verfasst von: Kauczor, Hans-Ulrich [VerfasserIn]
• Titel: High-resolution 3D unenhanced ECG-gated respiratory-navigated MR angiography of the renal arteries
• Titelzusatz: comparison with contrast-enhanced MR angiography
• Verf.angabe: Oliver K. Mohrs, Steffen E. Petersen, Thomas Schulze, Michael Zieschang, Harald Küx, Peter Schmitt, Sabine Bergemann and Hans-Ulrich Kauczor
• Jahr: 2010
• Umfang: 6 S.
• Fussnoten: Gesehen am 28.04.2023
• Titel Quelle: Enthalten in: American journal of roentgenology
• Ort Quelle: Leesburg, Va. : American Roentgen Ray Society, 1965
• Jahr Quelle: 2010
• Band/Heft Quelle: 195(2010), 6 vom: Okt., Seite 1423-1428
• ISSN Quelle: 1546-3141
• DOI: doi:10.2214/AJR.10.4365
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: contrast agent
• Sach-SW: MR angiography
• Sach-SW: peripheral artery disease
• Sach-SW: renal artery
• Sach-SW: unenhanced
• K10plus-PPN: 1843789930

Abstract

OBJECTIVE. The aim of this study is to determine the diagnostic value of high-resolution 3D unenhanced ECG-gated respiratory-navigated MR angiography (MRA) of the renal arteries using a steady-state free precession (SSFP) technique in comparison with 1.0-molar contrast-enhanced MRA in patients with suspected renal artery stenosis. - - SUBJECTS AND METHODS. Forty-five consecutive patients underwent unenhanced MRA before contrast-enhanced MRA within the same session. We assessed examination time, image quality, renal artery architecture, and localization and severity of renal artery stenosis. - - RESULTS. Examination time was shorter for contrast-enhanced MRA (mean ± SD, 12 ± 3 minutes) than for unenhanced MRA (19 ± 3 minutes; p < 0.001). On a 5-point scale, the image quality was similar for contrast-enhanced MRA (3.8 ± 1.0) and unenhanced MRA (4.0 ± 1.3; p = 0.24). Contrast-enhanced MRA offered more assessable data sets than did unenhanced MRA (95% vs 90%); however, unenhanced MRA had more data sets with maximum image quality (49% vs 30%). There was moderate agreement in stenosis grading between both MRA techniques (κ = 0.51; p < 0.001), but in only one case (1.3%) we found mismatch of more than one severity stenosis grade (stenoses > 75%). Sensitivity, specificity, and positive and negative predictive values of unenhanced MRA to detect renal artery stenoses greater than 50% were 75%, 99%, 75%, and 99%, respectively. - - CONCLUSION. We show that SSFP 3D unenhanced MRA is a very promising technique for patients with suspected renovascular disease and could be used as an alternative if gadolinium-based contrast agents cannot be administered.