| |  Online-Ressource |
|---|
| Verfasst von: | Riedel, Michael [VerfasserIn]  |
|---|
| | Möller, Hans-Jürgen [VerfasserIn] |
|---|
| | Obermeier, Michael [VerfasserIn] |
|---|
| | Schennach-Wolff, Rebecca [VerfasserIn] |
|---|
| | Bauer, Michael [VerfasserIn] |
|---|
| | Adli, Mazda [VerfasserIn] |
|---|
| | Kronmüller, Klaus-Thomas [VerfasserIn] |
|---|
| | Nickel, Thomas [VerfasserIn] |
|---|
| | Brieger, Peter [VerfasserIn] |
|---|
| | Laux, Gerd [VerfasserIn] |
|---|
| | Bender, Wolfram [VerfasserIn] |
|---|
| | Heuser, Isabella [VerfasserIn] |
|---|
| | Zeiler, Joachim [VerfasserIn] |
|---|
| | Gaebel, Wolfgang [VerfasserIn] |
|---|
| | Seemüller, Florian [VerfasserIn] |
|---|
| Titel: | Response and remission criteria in major depression - a validation of current practice |
|---|
| Verf.angabe: | Michael Riedel, Hans-Jürgen Möller, Michael Obermeier, Rebecca Schennach-Wolff, Michael Bauer, Mazda Adli, Klaus Kronmüller, Thomas Nickel, Peter Brieger, Gerd Laux, Wolfram Bender, Isabella Heuser, Joachim Zeiler, Wolfgang Gaebel, Florian Seemüller |
|---|
| E-Jahr: | 2010 |
|---|
| Jahr: | 5 May 2010 |
|---|
| Umfang: | 6 S. |
|---|
| Fussnoten: | Gesehen am 15.05.2023 |
|---|
| Titel Quelle: | Enthalten in: Journal of psychiatric research |
|---|
| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1961 |
|---|
| Jahr Quelle: | 2010 |
|---|
| Band/Heft Quelle: | 44(2010), 15 vom: Mai, Seite 1063-1068 |
|---|
| ISSN Quelle: | 1879-1379 |
|---|
| Abstract: | Remission and response were suggested as the most relevant outcome criteria for the treatment of depression. There is still marked uncertainty as to what cut-offs should be used on current depression rating scales. The goal of the present study was to compare the validity of different HAMD, MADRS and BDI cut-offs for response and remission. The naturalistic prospective study was performed in 12 psychiatric hospitals in Germany. All evaluable patients (n=846) were hospitalized and had to meet DSM-IV criteria for major depressive disorder. Biweekly ratings were assessed using HAMD-21, MADRS and BDI. A CGI-S score of 1 and a CGI-I score of at least 2 was used as the primary comparative measure of remission and response, respectively. A HAMD-21 cut-off≤7 (AUC: 0.92), HAMD-17 cut-of≤6 (AUC: 0.90), MADRS cut-off≤7 (AUC: 0.94) and BDI cut-off≤12 (AUC: 0.83) were associated with a maximum of specificity and sensitivity for defining remission. A minimum decrease of 47% of the HAMD-21 (AUC: 0.90), ≤57% for HAMD-17 (AUC: 0.89), ≤ 46% for MADRS (0.91) and a decrease of 47% for the BDI baseline score (AUC: 0.78) best corresponded CGI response criteria. Our data largely confirmed currently used remission and response criteria in naturalistically treated patients. |
|---|
| DOI: | doi:10.1016/j.jpsychires.2010.03.006 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.jpsychires.2010.03.006 |
|---|
| | Volltext: https://www.sciencedirect.com/science/article/pii/S0022395610000750 |
|---|
| | DOI: https://doi.org/10.1016/j.jpsychires.2010.03.006 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | BDI |
|---|
| | Bipolar |
|---|
| | CGI |
|---|
| | Cut-off |
|---|
| | HAMD-17 |
|---|
| | HMD-21 |
|---|
| | Inpatients |
|---|
| | MADRS |
|---|
| | Major depression |
|---|
| | Remission |
|---|
| | Response |
|---|
| K10plus-PPN: | 1845403320 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Response and remission criteria in major depression - a validation of current practice / Riedel, Michael [VerfasserIn]; 5 May 2010 (Online-Ressource)
