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| Verfasst von: | Tóth, Krisztina [VerfasserIn]  |
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| | Fresilli, Stefano [VerfasserIn] |
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| | Paoli, Nicola [VerfasserIn] |
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| | Maiucci, Giacomo [VerfasserIn] |
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| | Salvioni, Mariateresa [VerfasserIn] |
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| | Kotani, Yuki [VerfasserIn] |
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| | Katzenschlager, Stephan [VerfasserIn] |
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| | Weigand, Markus A. [VerfasserIn] |
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| | Landoni, Giovanni [VerfasserIn] |
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| Titel: | D-dimer levels in non-COVID-19 ARDS and COVID-19 ARDS patients |
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| Titelzusatz: | a systematic review with meta-analysis |
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| Verf.angabe: | Krisztina Tóth, Stefano Fresilli, Nicola Paoli, Giacomo Maiucci, Mariateresa Salvioni, Yuki Kotani, Stephan Katzenschlager, Markus A. Weigand, Giovanni Landoni |
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| E-Jahr: | 2023 |
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| Jahr: | February 6, 2023 |
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| Umfang: | 10 S. |
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| Fussnoten: | Gesehen am 12.06.2023 |
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| Titel Quelle: | Enthalten in: PLOS ONE |
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| Ort Quelle: | San Francisco, California, US : PLOS, 2006 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 18(2023), 2 vom: Feb., Artikel-ID e0277000, Seite 1-10 |
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| ISSN Quelle: | 1932-6203 |
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| Abstract: | Background Hypercoagulability and thrombo-inflammation are the main reasons for death in COVID-19 patients. It is unclear whether there is a difference between D-dimer levels in patients without or with COVID-19 acute respiratory distress syndrome (ARDS). Methods We searched PubMed, EMBASE, and ClinicalTrails.gov databases looking for studies reporting D-dimer levels in patients without or with COVID-19 ARDS. Secondary endpoints included length of hospital stay, and mortality data at the longest follow-up available. Results We included 12 retrospective and 3 prospective studies with overall 2,828 patients, of whom 1,404 (49.6%) had non-COVID-19 ARDS and 1,424 had COVID-19 ARDS. D-dimer levels were not significantly higher in non-COVID-19 ARDS than in COVID-19 ARDS patients (mean 7.65 mg/L vs. mean 6.20 mg/L MD 0.88 [CI: -0.61 to 2.38] p = 0.25; I² = 85%) while the length of hospital stay was shorter (non-COVID-19 mean 37.4 days vs. COVID-19 mean 48.5 days, MD -10.92 [CI: -16.71 to -5.14] p < 0.001; I² = 44%). No difference in mortality was observed: non-COVID-19 ARDS 418/1167 (35.8%) vs. COVID-19 ARDS 467/1201 (38.8%). Conclusions We found no difference in the mean D-dimer levels between non-COVID-19 ARDS and COVID-19 ARDS patients. |
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| DOI: | doi:10.1371/journal.pone.0277000 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1371/journal.pone.0277000 |
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| | kostenfrei: Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0277000 |
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| | DOI: https://doi.org/10.1371/journal.pone.0277000 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Acute respiratory distress syndrome |
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| | COVID 19 |
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| | Death rates |
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| | Hospitals |
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| | Intensive care units |
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| | Medical risk factors |
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| | Metaanalysis |
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| | Systematic reviews |
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| K10plus-PPN: | 1848782519 |
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| Verknüpfungen: | → Zeitschrift |
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D-dimer levels in non-COVID-19 ARDS and COVID-19 ARDS patients / Tóth, Krisztina [VerfasserIn]; February 6, 2023 (Online-Ressource)
