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| Verfasst von: | Erlmeier, Maximilian [VerfasserIn]  |
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| | Mikuteit, Marie [VerfasserIn] |
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| | Zschäbitz, Stefanie [VerfasserIn] |
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| | Autenrieth, Michael [VerfasserIn] |
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| | Weichert, Wilko [VerfasserIn] |
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| | Hartmann, Arndt [VerfasserIn] |
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| | Steffens, Sandra [VerfasserIn] |
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| | Erlmeier, Franziska [VerfasserIn] |
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| Titel: | Immunohistochemical expression of the hepatocyte growth factor in chromophobe renal cell carcinoma |
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| Verf.angabe: | Maximilian Erlmeier, Marie Mikuteit, Stefanie Zschäbitz, Michael Autenrieth, Wilko Weichert, Arndt Hartmann, Sandra Steffens and Franziska Erlmeier |
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| E-Jahr: | 2023 |
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| Jahr: | 11 May 2023 |
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| Umfang: | 6 S. |
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| Fussnoten: | Gesehen am 14.06.2023 |
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| Titel Quelle: | Enthalten in: BMC urology |
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| Ort Quelle: | London : BioMed Central, 2001 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 23(2023) vom: Mai, Artikel-ID 90, Seite 1-8 |
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| ISSN Quelle: | 1471-2490 |
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| Abstract: | Background: The prognostic value of Hepatocyte growth factor (HGF) in non-clear cell renal cell carcinoma (RCC) is still unclear. The aim of this study is to evaluate the prognostic impact of HGF expression in a large cohort of chromophobe RCC (chRCC). Methods: Patients who underwent renal surgery due to chRCC were recruited. Clinical data was retrospectively evaluated. Tumor specimen were analyzed for HGF expression by immunohistochemistry. Results: 81 chRCC patients were eligible for analysis, thereof 37 (45.7%) patients were positive for HGF. No significant associations were found for HGF expression and clinical attributes in patients with chRCC. Kaplan-Meier analysis revealed no differences in 5-year overall survival (OS) for patients with HGF− compared to HGF+ tumors (95.0% versus 90.9%; p = 0.410). Conclusions: In chRCC HGF expression is not associated with parameters of aggressiveness or survival. |
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| DOI: | doi:10.1186/s12894-023-01263-0 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1186/s12894-023-01263-0 |
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| | DOI: https://doi.org/10.1186/s12894-023-01263-0 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Chromophobe histology |
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| | HGF |
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| | Renal Cell Carcinoma |
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| | Survival |
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| K10plus-PPN: | 1848967586 |
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| Verknüpfungen: | → Zeitschrift |
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Immunohistochemical expression of the hepatocyte growth factor in chromophobe renal cell carcinoma / Erlmeier, Maximilian [VerfasserIn]; 11 May 2023 (Online-Ressource)
