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| Verfasst von: | Lebovka, Ivan [VerfasserIn]  |
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| | Hay Mele, Bruno [VerfasserIn] |
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| | Liu, Xiaomin [VerfasserIn] |
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| | Zakieva, Alexandra [VerfasserIn] |
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| | Schlamp, Theresa [VerfasserIn] |
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| | Gursanscky, Nial Rau [VerfasserIn] |
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| | Merks, Roeland MH [VerfasserIn] |
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| | Großeholz, Ruth [VerfasserIn] |
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| | Greb, Thomas [VerfasserIn] |
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| Titel: | Computational modeling of cambium activity provides a regulatory framework for simulating radial plant growth |
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| Verf.angabe: | Ivan Lebovka, Bruno Hay Mele, Xiaomin Liu, Alexandra Zakieva, Theresa Schlamp, Nial Rau Gursanscky, Roeland MH Merks, Ruth Großeholz, Thomas Greb |
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| E-Jahr: | 2023 |
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| Jahr: | 10 March 2023 |
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| Umfang: | 37 S. |
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| Fussnoten: | Gesehen am 21.06.2023 |
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| Titel Quelle: | Enthalten in: eLife |
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| Ort Quelle: | Cambridge : eLife Sciences Publications, 2012 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 12(2023) vom: März, Artikel-ID e66627, Seite 1-37 |
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| ISSN Quelle: | 2050-084X |
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| Abstract: | Precise organization of growing structures is a fundamental process in developmental biology. In plants, radial growth is mediated by the cambium, a stem cell niche continuously producing wood (xylem) and bast (phloem) in a strictly bidirectional manner. While this process contributes large parts to terrestrial biomass, cambium dynamics eludes direct experimental access due to obstacles in live-cell imaging. Here, we present a cell-based computational model visualizing cambium activity and integrating the function of central cambium regulators. Performing iterative comparisons of plant and model anatomies, we conclude that the receptor-like kinase PXY and its ligand CLE41 are part of a minimal framework sufficient for instructing tissue organization. By integrating tissue-specific cell wall stiffness values, we moreover probe the influence of physical constraints on tissue geometry. Our model highlights the role of intercellular communication within the cambium and shows that a limited number of factors are sufficient to create radial growth by bidirectional tissue production. |
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| DOI: | doi:10.7554/eLife.66627 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.7554/eLife.66627 |
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| | DOI: https://doi.org/10.7554/eLife.66627 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | computational biology |
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| | organ growth |
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| | stem cell regulation |
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| | wood formation |
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| K10plus-PPN: | 1850729794 |
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| Verknüpfungen: | → Zeitschrift |
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Computational modeling of cambium activity provides a regulatory framework for simulating radial plant growth / Lebovka, Ivan [VerfasserIn]; 10 March 2023 (Online-Ressource)
