Status: Bibliographieeintrag
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| Verfasst von: | Sertel, Serkan [VerfasserIn]  |
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| | Plinkert, Peter K. [VerfasserIn] |
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| | Efferth, Thomas [VerfasserIn] |
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| Titel: | Natural products derived from traditional chinese medicine as novel inhibitors of the epidermal growth factor receptor |
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| Verf.angabe: | Serkan Sertel, Peter K. Plinkert and Thomas Efferth |
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| Jahr: | 2010 |
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| Umfang: | 6 S. |
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| Fussnoten: | Gesehen am 29.06.2023 |
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| Titel Quelle: | Enthalten in: Combinatorial chemistry & high throughput screening |
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| Ort Quelle: | Hilversum [u.a.] : Bentham Science Publ., 1998 |
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| Jahr Quelle: | 2010 |
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| Band/Heft Quelle: | 13(2010), 10, Seite 849-854 |
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| ISSN Quelle: | 1875-5402 |
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| Abstract: | The epidermal growth factor receptor (EGFR) has become an important molecular target in cancer therapy. Various small molecules and therapeutic antibodies targeting EGFR family members have been developed during recent years and are established in clinical oncology. However, increasing - clinical application of EGFR tyrosine kinase inhibitors has resulted in the development of resistance to EGFR-targeting drugs due to the selection of EGFR-mutated variants. This phenomenon forced the search for novel EGFR inhibitors with activity towards EGFR-mutant tumors. This review describes - recent achievements in natural products derived from medicinal plants as novel EGFR inhibitors. |
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| DOI: | doi:10.2174/138620710793360266 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
DOI: https://doi.org/10.2174/138620710793360266 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Artemisia annua |
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| | camptothecin |
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| | Cancer |
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| | cell lung carcinoma |
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| | cephalotaxine |
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| | Cephalotaxus hainanensis |
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| | CET |
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| | CPT |
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| | drug resistance |
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| | EGFR tyrosine kinase inhibitor |
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| | epidermal growth factor receptor (EGFR) |
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| | ester homoharringtonine |
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| | head and neck squamous cell cancer |
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| | HNSCC |
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| | Lithospermum erythrorhizon |
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| | Lithospermum radix |
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| | Magnolia officinalis |
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| | Magnoliae Cortex |
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| | medicinal plant |
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| | natural product |
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| | non-small cell carcinoma |
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| | NSCLC |
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| | Oral squamous cell carcinoma |
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| | OSCC |
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| | ovarian cancer |
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| | paclitaxel |
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| | Rabdosia rubescens |
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| | renal cancer |
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| | SCC |
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| | SCLC |
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| | small cell carcinoma |
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| | small cell lung carcinoma |
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| | vinblastine |
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| | vincristine |
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| K10plus-PPN: | 1851239510 |
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| Verknüpfungen: | → Zeitschrift |
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Natural products derived from traditional chinese medicine as novel inhibitors of the epidermal growth factor receptor / Sertel, Serkan [VerfasserIn]; 2010 (Online-Ressource)
69091162
