Regulation patterns in signaling networks of cancer

• Verfasst von: Schramm, Gunnar [VerfasserIn]
• Verfasst von: Nandakumar, Kannabiran [VerfasserIn]
• Verfasst von: König, Rainer [VerfasserIn]
• Titel: Regulation patterns in signaling networks of cancer
• Verf.angabe: Gunnar Schramm, Nandakumar Kannabiran, Rainer König
• E-Jahr: 2010
• Jahr: 26 November 2010
• Umfang: 12 S.
• Fussnoten: Gesehen am 29.06.2023
• Titel Quelle: Enthalten in: BMC systems biology
• Ort Quelle: London : BioMed Central, 2007
• Jahr Quelle: 2010
• Band/Heft Quelle: 4(2010), 1, Artikel-ID 162, Seite 1-12
• ISSN Quelle: 1752-0509
• DOI: doi:10.1186/1752-0509-4-162
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Acute Myeloid Leukemia
• Sach-SW: Cancer Sample
• Sach-SW: Cluster Coefficient
• Sach-SW: Esophageal Squamous Cell Carcinoma
• Sach-SW: Short Path
• K10plus-PPN: 1851251227

Abstract

Formation of cellular malignancy results from the disruption of fine tuned signaling homeostasis for proliferation, accompanied by mal-functional signals for differentiation, cell cycle and apoptosis. We wanted to observe central signaling characteristics on a global view of malignant cells which have evolved to selfishness and independence in comparison to their non-malignant counterparts that fulfill well defined tasks in their sample.