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Verfasst von:Schwenger, Vedat [VerfasserIn]   i
 Morath, Christian [VerfasserIn]   i
Titel:Immunoadsorption in nephrology and kidney transplantation
Verf.angabe:Vedat Schwenger and Christian Morath
E-Jahr:2010
Jahr:14 May 2010
Umfang:7 S.
Fussnoten:Gesehen am 11.07.2023
Titel Quelle:Enthalten in: Nephrology, dialysis, transplantation
Ort Quelle:Oxford : Oxford Univ. Press, 1986
Jahr Quelle:2010
Band/Heft Quelle:25(2010), 8 vom: Aug., Seite 2407-2413
ISSN Quelle:1460-2385
Abstract:Immunoadsorption finds incremental implementation in the treatment of several autoimmune disorders as well as for kidney transplant indications (see Table 1). As opposed to plasmapheresis, immunoadsorption allows not only a more specific but also a more effective clearance of circulating immunoglobulins without the side effects associated with the substitution of fresh frozen plasma or albumin. In addition, even multiple plasma volumes may be processed, and a reduction of immunoglobulins of 80% and more is feasible [1]. However, one has to consider that plasmapheresis is not only utilized for removal of immunoglobulins but also for the substitution of different plasma components such as ADAMTS-13 in the case of thrombotic thrombocytopenic purpura [2]. Therefore, plasma infusion itself may have beneficial effects independent of the removal of circulating pathogenic substances. The use of plasmapheresis for the treatment of different kidney diseases remains controversial due to a lack of randomized controlled trials demonstrating the benefit of this procedure. This applies even more to immunoadsorption. However, for some indications especially in the field of kidney transplantation, there is now growing evidence pointing to the large potential of this treatment modality. This editorial comment will focus on the available evidence on immunoadsorption in kidney diseases and kidney transplant indications.
DOI:doi:10.1093/ndt/gfq264
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1093/ndt/gfq264
 Volltext: https://academic.oup.com/ndt/article/25/8/2407/1899255?login=true
 DOI: https://doi.org/10.1093/ndt/gfq264
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1852334053
Verknüpfungen:→ Zeitschrift

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