| Online-Ressource |
Verfasst von: | Asare, Kwabena [VerfasserIn]  |
| Ngcapu, Sinaye [VerfasserIn]  |
| Osman, Farzana [VerfasserIn]  |
| Vandormael, Alain [VerfasserIn]  |
| Mindel, Adrian [VerfasserIn]  |
| Naicker, Nivashnee [VerfasserIn]  |
| Khanyile, Mlungisi [VerfasserIn]  |
| S. Abdool Karim, Salim [VerfasserIn]  |
| Tomita, Andrew [VerfasserIn]  |
| Garrett, Nigel [VerfasserIn]  |
Titel: | Incidence, recurrence, and prevalence of bacterial vaginosis from acute to chronic HIV infection in a prospective cohort of women in South Africa |
Verf.angabe: | Kwabena Asare, Sinaye Ngcapu, Farzana Osman, Alain Vandormael, Adrian Mindel, Nivashnee Naicker, Mlungisi Khanyile, Salim S. Abdool Karim, Andrew Tomita, Nigel Garrett |
E-Jahr: | 2023 |
Jahr: | June 2023 |
Umfang: | 7 S. |
Fussnoten: | Online verfügbar 8. April 2023, Artikelversion 5. Mai 2023 ; Gesehen am 21.07.2023 |
Titel Quelle: | Enthalten in: Annals of epidemiology |
Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1990 |
Jahr Quelle: | 2023 |
Band/Heft Quelle: | 82(2023) vom: Juni, Seite 33-39 |
ISSN Quelle: | 1873-2585 |
Abstract: | Purpose - We investigated the incidence, recurrence, prevalence, and risk factors for bacterial vaginosis (BV) diagnosis starting from acute HIV infection among South African women. - Methods - The Centre for the AIDS Programme of Research in South Africa 002 study tested and treated women for BV (Nugent score 7-10) once/twice annually from acute to chronic HIV infection (2004-2020). We estimated BV incidence as the number of new cases and recurrence as the number of subsequent diagnoses per 100 person-years (PYs). We fitted Anderson-Gil Cox-proportional-hazard regression models to determine factors associated with BV incidence or recurrence. - Results - Of 235 participants, the median age at enrollment was 25 years (Inter Quartile Range [IQR] 22-29). BV prevalence at enrollment was 50.6%. BV incidence was 23.9 cases per 100 PYs, and recurrence was 51.3 cases per 100 PYs. BV incidence/recurrence was associated with younger age (<25 years: adjusted hazard ratio [aHR] 1.70, 95% confidence interval [CI] 1.27-2.27), detectable HIV viral load (aHR 1.54, 95% CI 1.27-1.87) and lower CD4 count (<350 cells/μL: aHR 1.33, 95% CI 1.01-1.76). - Conclusions - Our findings underscore the need for early antiretroviral treatment initiation with diagnostic BV and sexually transmitted infection care, especially among younger women. |
DOI: | doi:10.1016/j.annepidem.2023.04.004 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.annepidem.2023.04.004 |
| Volltext: https://www.sciencedirect.com/science/article/pii/S1047279723000613 |
| DOI: https://doi.org/10.1016/j.annepidem.2023.04.004 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Acute HIV infection |
| Bacterial vaginosis |
| Human immunodeficiency virus |
| Women living with HIV |
K10plus-PPN: | 1853324957 |
Verknüpfungen: | → Zeitschrift |
Incidence, recurrence, and prevalence of bacterial vaginosis from acute to chronic HIV infection in a prospective cohort of women in South Africa / Asare, Kwabena [VerfasserIn]; June 2023 (Online-Ressource)