| |  Online-Ressource |
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| Verfasst von: | Morgenstern, Jakob [VerfasserIn]  |
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| | Gröner, Jan [VerfasserIn] |
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| | Jende, Johann [VerfasserIn] |
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| | Kurz, Felix T. [VerfasserIn] |
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| | Strom, Alexander [VerfasserIn] |
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| | Göpfert, Jens Christian [VerfasserIn] |
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| | Kender, Zoltán [VerfasserIn] |
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| | Le Marois, Maxime [VerfasserIn] |
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| | Brune, Maik [VerfasserIn] |
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| | Kuner, Rohini [VerfasserIn] |
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| | Herzig, Stephan [VerfasserIn] |
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| | Roden, Michael [VerfasserIn] |
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| | Ziegler, Dan [VerfasserIn] |
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| | Bendszus, Martin [VerfasserIn] |
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| | Szendrödi, Julia [VerfasserIn] |
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| | Nawroth, Peter Paul [VerfasserIn] |
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| | Kopf, Stefan [VerfasserIn] |
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| | Fleming, Thomas [VerfasserIn] |
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| Titel: | Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy |
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| Verf.angabe: | Jakob Morgenstern, Jan B. Groener, Johann M. E. Jende, Felix T. Kurz, Alexander Strom, Jens Göpfert, Zoltan Kender, Maxime Le Marois, Maik Brune, Rohini Kuner, Stephan Herzig, Michael Roden, Dan Ziegler, Martin Bendszus, Julia Szendroedi, Peter Nawroth, Stefan Kopf, Thomas Fleming |
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| E-Jahr: | 2021 |
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| Jahr: | 03 September 2021 |
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| Umfang: | 13 S. |
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| Fussnoten: | Gesehen am 28.07.2023 |
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| Titel Quelle: | Enthalten in: Diabetologia |
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| Ort Quelle: | Berlin : Springer, 1965 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 64(2021), 12, Seite 2843-2855 |
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| ISSN Quelle: | 1432-0428 |
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| Abstract: | The individual risk of progression of diabetic peripheral neuropathy is difficult to predict for each individual. Mutations in proteins that are responsible for the process of myelination are known to cause neurodegeneration and display alteration in experimental models of diabetic neuropathy. In a prospective observational human pilot study, we investigated myelin-specific circulating mRNA targets, which have been identified in vitro, for their capacity in the diagnosis and prediction of diabetic neuropathy. The most promising candidate was tested against the recently established biomarker of neural damage, neurofilament light chain protein. |
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| DOI: | doi:10.1007/s00125-021-05557-6 |
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| URL: | kostenfrei: Volltext: https://doi.org/10.1007/s00125-021-05557-6 |
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| | DOI: https://doi.org/10.1007/s00125-021-05557-6 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Biomarker |
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| | Myelin protein zero |
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| | Myelination |
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| | Neurofilament light chain |
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| | Peripheral neuropathy |
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| K10plus-PPN: | 1853885169 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy / Morgenstern, Jakob [VerfasserIn]; 03 September 2021 (Online-Ressource)
