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| Verfasst von: | Görtz, Magdalena [VerfasserIn]  |
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| | Huber, Ann-Kathrin [VerfasserIn] |
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| | Linz, Tim [VerfasserIn] |
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| | Schwab, Constantin [VerfasserIn] |
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| | Stenzinger, Albrecht [VerfasserIn] |
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| | Goertz, Lukas [VerfasserIn] |
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| | Bonekamp, David [VerfasserIn] |
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| | Schlemmer, Heinz-Peter [VerfasserIn] |
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| | Hohenfellner, Markus [VerfasserIn] |
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| Titel: | Detection rate of prostate cancer in repeat biopsy after an initial negative magnetic resonance imaging/ultrasound-guided biopsy |
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| Verf.angabe: | Magdalena Görtz, Ann-Kathrin Huber, Tim Linz, Constantin Schwab, Albrecht Stenzinger, Lukas Goertz, David Bonekamp, Heinz-Peter Schlemmer and Markus Hohenfellner |
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| E-Jahr: | 2023 |
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| Jahr: | 17 May 2023 |
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| Umfang: | 16 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 30.11.2023 |
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| Titel Quelle: | Enthalten in: Diagnostics |
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| Ort Quelle: | Basel : MDPI, 2011 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 13(2023), 10, Artikel-ID 1761, Seite 1-16 |
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| ISSN Quelle: | 2075-4418 |
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| Abstract: | A negative multiparametric magnetic resonance imaging (mpMRI)-guided prostate biopsy in patients with suspected prostate cancer (PC) results in clinical uncertainty, as the biopsy can be false negative. The clinical challenge is to determine the optimal follow-up and to select patients who will benefit from repeat biopsy. In this study, we evaluated the rate of significant PC (sPC, Gleason score ≥7) and PC detection in patients who received a follow-up mpMRI/ultrasound-guided biopsy for persistent PC suspicion after a negative mpMRI/ultrasound-guided biopsy. We identified 58 patients at our institution that underwent repeat targeted biopsy in case of PI-RADS lesions and systematic saturation biopsy between 2014 and 2022. At the initial biopsy, the median age was 59 years, and the median prostate specific antigen level was 6.7 ng/mL. Repeat biopsy after a median of 18 months detected sPC in 3/58 (5%) patients and Gleason score 6 PC in 11/58 (19%). Among 19 patients with a downgraded PI-RADS score at the follow-up mpMRI, none had sPC. In conclusion, men with an initial negative mpMRI/ultrasound-guided biopsy had a high likelihood of not harboring sPC at repeat biopsy (95%). Due to the small size of the study, further research is recommended. |
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| DOI: | doi:10.3390/diagnostics13101761 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/diagnostics13101761 |
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| | kostenfrei: Volltext: https://www.mdpi.com/2075-4418/13/10/1761 |
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| | DOI: https://doi.org/10.3390/diagnostics13101761 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | magnetic resonance imaging |
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| | MRI/TRUS fusion biopsy |
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| | PI-RADS |
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| | prostate cancer |
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| | prostate-specific antigen |
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| K10plus-PPN: | 1853912441 |
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| Verknüpfungen: | → Zeitschrift |
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Detection rate of prostate cancer in repeat biopsy after an initial negative magnetic resonance imaging/ultrasound-guided biopsy / Görtz, Magdalena [VerfasserIn]; 17 May 2023 (Online-Ressource)
