Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Algra, Annemijn M. [VerfasserIn]   i
 Greving, Jacoba P. [VerfasserIn]   i
 Winkel, Jordi de [VerfasserIn]   i
 Kurtelius, Arttu [VerfasserIn]   i
 Laban, Kamil [VerfasserIn]   i
 Verbaan, Dagmar [VerfasserIn]   i
 Berg, René van den [VerfasserIn]   i
 Vandertop, William [VerfasserIn]   i
 Lindgren, Antti [VerfasserIn]   i
 Krings, Timo [VerfasserIn]   i
 Woo, Peter Y. M. [VerfasserIn]   i
 Wong, George K. C. [VerfasserIn]   i
 Roozenbeek, Bob [VerfasserIn]   i
 Es, Adriaan C. G. M. van [VerfasserIn]   i
 Dammers, Ruben [VerfasserIn]   i
 Etminan, Nima [VerfasserIn]   i
 Boogaarts, Hieronymus [VerfasserIn]   i
 Doormaal, Tristan van [VerfasserIn]   i
 Zwan, Albert van der [VerfasserIn]   i
 Schaaf, Irene C. van der [VerfasserIn]   i
 Rinkel, Gabriël J. E. [VerfasserIn]   i
 Vergouwen, Mervyn D. I. [VerfasserIn]   i
Titel:Development of the SAFETEA scores for predicting risks of complications of preventive endovascular or microneurosurgical intracranial aneurysm occlusion
Verf.angabe:Annemijn M. Algra, Jacoba P. Greving, Jordi de Winkel, Arttu Kurtelius, Kamil Laban, Dagmar Verbaan, René van den Berg, William Vandertop, Antti Lindgren, Timo Krings, Peter Y.M. Woo, George K.C. Wong, Bob Roozenbeek, Adriaan C.G.M. van Es, Ruben Dammers, Nima Etminan, Hieronymus Boogaarts, Tristan van Doormaal, Albert van der Zwan, Irene C. van der Schaaf, Gabriël J.E. Rinkel, FRCPE, and Mervyn D.I. Vergouwen
E-Jahr:2022
Jahr:September 2, 2022
Umfang:15 S.
Fussnoten:Gesehen am 01.08.2023
Titel Quelle:Enthalten in: Neurology
Ort Quelle:Philadelphia, Pa. : Wolters Kluwer, 1951
Jahr Quelle:2022
Band/Heft Quelle:99(2022), 16 vom: Okt., Seite e1725-e1737
ISSN Quelle:1526-632X
Abstract:Background and Objectives Preventive unruptured intracranial aneurysm (UIA) occlusion can reduce the risk of subarachnoid hemorrhage, but both endovascular and microneurosurgical treatment carry a risk of serious complications. To improve individualized management decisions, we developed risk scores for complications of endovascular and microneurosurgical treatment based on easily retrievable patient, aneurysm, and treatment characteristics. - Methods For this multicenter cohort study, we combined individual patient data from patients with UIA aged 18 years or older undergoing preventive endovascular treatment (standard, balloon-assisted or stent-assisted coiling, Woven EndoBridge-device, or flow-diverting stent) or microneurosurgical clipping at one of the 10 participating centers from 3 continents between 2000 and 2018. The primary outcome was death from any cause or clinical deterioration from neurologic complications ≤30 days. We selected predictors based on previous knowledge about relevant risk factors and predictor performance and studied the association between predictors and complications with logistic regression. We assessed model performance with calibration plots and concordance (c) statistics. - Results Of the 1,282 included patients, 94 (7.3%) had neurologic symptoms that resolved <30 days, 140 (10.9%) had persisting neurologic symptoms, and 6 died (0.5%). At 30 days, 52 patients (4.1%) were dead or dependent. Predictors of procedural complications were size of aneurysm, aneurysm location, familial subarachnoid hemorrhage, earlier atherosclerotic disease, treatment volume, endovascular modality (for endovascular treatment) or extra aneurysm configuration factors (for microneurosurgical treatment, branching artery from aneurysm neck or unfavorable dome-to-neck ratio), and age (acronym: SAFETEA). For endovascular treatment (n = 752), the c-statistic was 0.72 (95% CI 0.67-0.77) and the absolute complication risk ranged from 3.2% (95% CI 1.6%-14.9%; ≤1 point) to 33.1% (95% CI 25.4%-41.5%; ≥6 points). For microneurosurgical treatment (n = 530), the c-statistic was 0.72 (95% CI 0.67-0.77) and the complication risk ranged from 4.9% (95% CI 1.5%-14.9%; ≤1 point) to 49.9% (95% CI 39.4%-60.6%; ≥6 points). - Discussion The SAFETEA risk scores for endovascular and microneurosurgical treatment are based on 7 easily retrievable risk factors to predict the absolute risk of procedural complications in patients with UIAs. The scores need external validation before the predicted risks can be properly used to support decision-making in clinical practice. - Classification of Evidence This study provides Class III evidence that SAFETEA scores predict the risk of procedural complications after endovascular and microneurosurgical treatment of unruptured intracranial aneurysms.
DOI:doi:10.1212/WNL.0000000000200978
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1212/WNL.0000000000200978
 Volltext: http://n.neurology.org/content/99/16/e1725
 DOI: https://doi.org/10.1212/WNL.0000000000200978
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1853993816
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/69103030   QR-Code
zum Seitenanfang