| Online-Ressource |
Verfasst von: | Derigs, Fabian [VerfasserIn]  |
| Doryumu, Samuel [VerfasserIn]  |
| Tollens, Fabian [VerfasserIn]  |
| Nörenberg, Dominik [VerfasserIn]  |
| Neuberger, Manuel [VerfasserIn]  |
| Hardenberg, Jost von [VerfasserIn]  |
| Michel, Maurice Stephan [VerfasserIn]  |
| Ritter, Manuel [VerfasserIn]  |
| Westhoff, Niklas Christian [VerfasserIn]  |
Titel: | A prospective study on inter-operator variability in semi-robotic software-based MRI/TRUS-fusion targeted prostate biopsies |
Verf.angabe: | Fabian Derigs, Samuel Doryumu, Fabian Tollens, Dominik Nörenberg, Manuel Neuberger, Jost Von Hardenberg, Maurice Stephan Michel, Manuel Ritter, Niklas Westhoff |
Jahr: | 2022 |
Umfang: | 7 S. |
Fussnoten: | Published online: 26 November 2021 ; Gesehen am 07.06.2023 |
Titel Quelle: | Enthalten in: World journal of urology |
Ort Quelle: | Berlin : Springer, 1983 |
Jahr Quelle: | 2022 |
Band/Heft Quelle: | 40(2022), 2, Seite 427-433 |
ISSN Quelle: | 1433-8726 |
Abstract: | Purpose Magnetic resonance imaging (MRI)/ultrasound-fusion prostate biopsy (FB) comprises multiple steps each of which can cause alterations in targeted biopsy (TB) accuracy leading to false-negative results. The aim was to assess the interoperator variability of software-based fusion TB by targeting the same MRI-lesions by different urologists. - Methods In this prospective study, 142 patients eligible for analysis underwent software-based FB. TB of all lesions (n = 172) were carried out by two different urologists per patient (n = 31 urologists). We analyzed the number of mismatches [overall prostate cancer (PCa), clinically significant PCa (csPCa) and non-significant PCa (nsPCa)] between both performed TB per patient. In addition we evaluated factors contributing to inter-operator variability by uni- and multivariable analyses. - Results In 11.6% of all MRI-lesions (10.6% of all patients) there was a mismatch between TB1 and TB2 in terms of overall prostate cancer (PCa detection. Regarding csPCa, patient-based mismatch occurred in 14.8% (n = 21). Overall PCa and csPCa detection rate of TB1 and TB2 did not differ significantly on a per-patient and per-lesion level. Analyses revealed a smaller lesion size as predictive for mismatches (OR 9.19, 95% CI 2.02-41.83, p < 0.001). - Conclusion Reproducibility and precision of targeting particularly small lesions is still limited although using software-based FB. Further improvements in image-fusion, segmentation, needle-guidance, and automatization are necessary. |
DOI: | doi:10.1007/s00345-021-03891-3 |
URL: | kostenfrei: Volltext: https://doi.org/10.1007/s00345-021-03891-3 |
| kostenfrei: Volltext: https://link.springer.com/10.1007/s00345-021-03891-3 |
| DOI: https://doi.org/10.1007/s00345-021-03891-3 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 184765889X |
Verknüpfungen: | → Zeitschrift |
|
|
| |
Lokale URL UB: | Zum Volltext |
¬A¬ prospective study on inter-operator variability in semi-robotic software-based MRI/TRUS-fusion targeted prostate biopsies / Derigs, Fabian [VerfasserIn]; 2022 (Online-Ressource)