Status: Bibliographieeintrag
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| Verfasst von: | Erlmeier, Franziska [VerfasserIn]  |
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| | Zschäbitz, Stefanie [VerfasserIn] |
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| | Mikuteit, Marie [VerfasserIn] |
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| | Autenrieth, Michael [VerfasserIn] |
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| | Weichert, Wilko [VerfasserIn] |
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| | Hartmann, Arndt [VerfasserIn] |
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| | Steffens, Sandra [VerfasserIn] |
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| Titel: | The role of claudin-6 in chromophobe renal cell carcinoma |
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| Verf.angabe: | Franziska Erlmeier, Stefanie Zschaebitz, Marie Mikuteit, Michael Autenrieth, Wilko Weichert, Arndt Hartmann and Sandra Steffens |
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| Jahr: | 2023 |
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| Umfang: | 5 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 14.08.2023 |
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| Titel Quelle: | Enthalten in: Histology and histopathology |
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| Ort Quelle: | Murcia : Francisco Hernández ; Juan F. Madrid, 1993 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 38(2023), 4, Seite 403-407 |
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| ISSN Quelle: | 1699-5848 |
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| Abstract: | Background. The prognostic value of Claudin-6 (CLDN6) in non clear cell renal cell carcinoma (RCC) is still unclear. Aim. To evaluate the prognostic impact of CLDN6 expression in a large cohort of chromophobe RCC (chRCC). Material and Methods. Patients who underwent renal surgery due to chRCC were recruited. Clinical data were retrospectively evaluated. Tumor specimens were analyzed for CLDN6 expression by immunohisto-chemistry. Results. 81 chRCC patients were eligible for analysis, thereof 10 (12.3%) patients were positive for CLDN6. No significant associations were found for CLDN6 expression and clinical attributes in patients with chRCC. Kaplan-Meier analysis revealed no differences in overall survival (OS) for patients with CLDN6- compared to CLDN6+ tumors (87.0% versus 62.5%; p=0.174). Conclusion. In chRCC CLDN6 expression is not associated with parameters of aggressiveness or survival. Due to the rare incidence of chRCC further studies with larger cohorts are warranted. |
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| DOI: | doi:10.14670/HH-18-520 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.14670/HH-18-520 |
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| | kostenfrei: Volltext: https://www.hh.um.es/Abstracts/Vol_38/38_4/38_4_403.htm |
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| | DOI: https://doi.org/10.14670/HH-18-520 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | CANCER |
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| | Chromophobe histology |
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| | Claudin-6 |
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| | DIAGNOSIS |
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| | EXPRESSION |
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| | MARKER |
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| | Renal Cell Carcinoma |
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| | Survival |
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| | TARGETS |
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| K10plus-PPN: | 1856097617 |
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| Verknüpfungen: | → Zeitschrift |
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¬The¬ role of claudin-6 in chromophobe renal cell carcinoma / Erlmeier, Franziska [VerfasserIn]; 2023 (Online-Ressource)
69112239
