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Verfasst von:Noh, Sangkyu [VerfasserIn]   i
 Nessim, Carolyn [VerfasserIn]   i
 Keung, Emily Z. [VerfasserIn]   i
 Roland, Christina L. [VerfasserIn]   i
 Strauss, Dirk [VerfasserIn]   i
 Sivarajah, Gausihi [VerfasserIn]   i
 Fiore, Marco [VerfasserIn]   i
 Biasoni, Davide [VerfasserIn]   i
 Cioffi, Stefano Piero Bernardo [VerfasserIn]   i
 Mehtsun, Winta [VerfasserIn]   i
 Cananzi, Ferdinando Carlo Maria [VerfasserIn]   i
 Sicoli, Federico [VerfasserIn]   i
 Quagliuolo, Vittorio [VerfasserIn]   i
 Chen, Jun [VerfasserIn]   i
 Luo, Chenghua [VerfasserIn]   i
 Gladdy, Rebecca A. [VerfasserIn]   i
 Swallow, Carol [VerfasserIn]   i
 Johnston, Wendy [VerfasserIn]   i
 Ford, Samuel J. [VerfasserIn]   i
 Evenden, Caroline [VerfasserIn]   i
 Tirotta, Fabio [VerfasserIn]   i
 Almond, Max [VerfasserIn]   i
 Nguyen, Laura [VerfasserIn]   i
 Rutkowski, Piotr [VerfasserIn]   i
 Krotewicz, Maria [VerfasserIn]   i
 Pennacchioli, Elisabetta [VerfasserIn]   i
 Cardona, Kenneth [VerfasserIn]   i
 Gamboa, Adriana [VerfasserIn]   i
 Hompes, Daphne [VerfasserIn]   i
 Renard, Marleen [VerfasserIn]   i
 Kollár, Attila [VerfasserIn]   i
 Ryser, Christoph O. [VerfasserIn]   i
 Vassos, Nikolaos [VerfasserIn]   i
 Raut, Chandrajit P. [VerfasserIn]   i
 Fairweather, Mark [VerfasserIn]   i
 Krakorova, Dagmar Adamkova [VerfasserIn]   i
 Quildrian, Sergio [VerfasserIn]   i
 Perhavec, Andraz [VerfasserIn]   i
 Nizri, Eran [VerfasserIn]   i
 Farma, Jeffrey M. [VerfasserIn]   i
 Greco, Stephanie H. [VerfasserIn]   i
 Vincenzi, Bruno [VerfasserIn]   i
 Lopez, José Antonio González [VerfasserIn]   i
 Solerdecoll, Mireia Solans [VerfasserIn]   i
 Iwata, Shintaro [VerfasserIn]   i
 Fukushima, Suguru [VerfasserIn]   i
 Kim, Teresa [VerfasserIn]   i
 Tolomeo, Francesco [VerfasserIn]   i
 Snow, Hayden [VerfasserIn]   i
 Howlett-Jansen, Ynez [VerfasserIn]   i
 Tzanis, Dimitri [VerfasserIn]   i
 Nikulin, Maxim [VerfasserIn]   i
 Gronchi, Alessandro [VerfasserIn]   i
 Sicklick, Jason K. [VerfasserIn]   i
Titel:Retrospective analysis of retroperitoneal-abdominal-pelvic ganglioneuromas
Titelzusatz:an international study by the Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)
Verf.angabe:Sangkyu Noh, Carolyn Nessim, Emily Z. Keung, Christina L. Roland, Dirk Strauss, Gausihi Sivarajah, Marco Fiore, Davide Biasoni, Stefano Piero Bernardo Cioffi, Winta Mehtsun, Ferdinando Carlo Maria Cananzi, Federico Sicoli, Vittorio Quagliuolo, Jun Chen, Chenghua Luo, Rebecca A. Gladdy, Carol Swallow, Wendy Johnston, Samuel J. Ford, Caroline Evenden, Fabio Tirotta, Max Almond, Laura Nguyen, Piotr Rutkowski, Maria Krotewicz, Elisabetta Pennacchioli, Kenneth Cardona, Adriana Gamboa, Daphne Hompes, Marleen Renard, Attila Kollár, Christoph O. Ryser, Nikolaos Vassos, Chandrajit P. Raut, Mark Fairweather, Dagmar Adamkova Krakorova, Sergio Quildrian, Andraz Perhavec, Eran Nizri, Jeffrey M. Farma, Stephanie H. Greco, Bruno Vincenzi, José Antonio González Lopez, Mireia Solans Solerdecoll, Shintaro Iwata, Suguru Fukushima, Teresa Kim, Francesco Tolomeo, Hayden Snow, Ynez Howlett-Jansen, Dimitri Tzanis, Maxim Nikulin, Alessandro Gronchi, Jason K. Sicklick, and on behalf of the Transatlantic Australasian Retroperitoneal Sarcoma Working Group
E-Jahr:2023
Jahr:August 2023
Umfang:7 S.
Fussnoten:Gesehen am 13.10.2023
Titel Quelle:Enthalten in: Annals of surgery
Ort Quelle:[Erscheinungsort nicht ermittelbar] : Lippincott Williams & Wilkins, 1885
Jahr Quelle:2023
Band/Heft Quelle:278(2023), 2 vom: Aug., Seite 267-273
ISSN Quelle:1528-1140
Abstract:Objective: - The Transatlantic Australasian Retroperitoneal Sarcoma Working Group conducted a retrospective study on the disease course and clinical management of ganglioneuromas. - Background: - Ganglioneuromas are rare tumors derived from neural crest cells. Data on these tumors remain limited to case reports and single-institution case series. - Methods: - Patients of all ages with pathologically confirmed primary retroperitoneal, intra-abdominal, and pelvic ganglioneuromas between January 1, 2000, and January 1, 2020, were included. We examined demographic, clinicopathologic, and radiologic characteristics, as well as clinical management. - Results: - Overall, 328 patients from 29 institutions were included. The median age at diagnosis was 37 years with 59.1% of patients being female. Symptomatic presentation comprised 40.9% of cases, and tumors were often located in the extra-adrenal retroperitoneum (67.1%). At baseline, the median maximum tumor diameter was 7.2 cm. One hundred sixteen (35.4%) patients underwent active surveillance, whereas 212 (64.6%) patients underwent resection with 74.5% of operative cases achieving an R0/R1 resection. Serial tumor evaluations showed that malignant transformation to neuroblastoma was rare (0.9%, N=3). Tumors undergoing surveillance had a median follow-up of 1.9 years, with 92.2% of ganglioneuromas stable in size. With a median follow-up of 3.0 years for resected tumors, 84.4% of patients were disease free after resections, whereas recurrences were observed in 4 (1.9%) patients. - Conclusions: - Most ganglioneuromas have indolent disease courses and rarely transform to neuroblastoma. Thus, active surveillance may be appropriate for benign and asymptomatic tumors particularly when the risks of surgery outweigh the benefits. For symptomatic or growing tumors, resection may be curative.
DOI:doi:10.1097/SLA.0000000000005625
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1097/SLA.0000000000005625
 Volltext: https://journals.lww.com/annalsofsurgery/fulltext/2023/08000/retrospective_analysis_of.18.aspx
 DOI: https://doi.org/10.1097/SLA.0000000000005625
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:186381096X
Verknüpfungen:→ Zeitschrift

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