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Verfasst von:Beyer, Thomas [VerfasserIn]   i
 Czernin, Johannes [VerfasserIn]   i
 Freudenberg, Lutz [VerfasserIn]   i
 Giesel, Frederik L. [VerfasserIn]   i
 Hacker, Marcus [VerfasserIn]   i
 Hicks, Rodney J. [VerfasserIn]   i
 Krause, Bernd J. [VerfasserIn]   i
Titel:A 2022 international survey on the status of prostate cancer theranostics
Verf.angabe:Thomas Beyer, Johannes Czernin, Lutz Freudenberg, Frederik Giesel, Marcus Hacker, Rodney J. Hicks, and Bernd J. Krause
E-Jahr:2023
Jahr:January 1, 2023
Umfang:7 S.
Fussnoten:Online veröffentlicht: 11. August 2022 ; Gesehen am 19.10.2023
Titel Quelle:Enthalten in: Journal of nuclear medicine
Ort Quelle:New York, NY : Soc., 1964
Jahr Quelle:2023
Band/Heft Quelle:64(2023), 1 vom: Jan., Seite 47-53
ISSN Quelle:2159-662X
 1535-5667
Abstract:Growing interest in PSMA imaging using [68Ga]- or [18F]-labeled ligands and PSMA-based radioligand therapy (RLT) of prostate cancer (PCa) prompted us to survey the global community on their experiences and expectations. Methods: A web-based survey was composed to interrogate areas specific to PET imaging, the clinical value chain, and RLT applications. International responses were collected in early 2022. In total, over 300 valid responses were received and evaluated. Results: Most responses (83%) were given by nuclear medicine specialists with extensive experience in PET. At 22% of sites, PCa ranked “top” in cancer-type–specific PET indications, with an average and median of 15% and 10% of all cases, respectively. The most frequently used PSMA PET tracers were [68Ga]PSMA (32%) and [18F]PSMA-1007 (31%). Users reported a steady growth in PSMA PET and RLT over the past 5 y, averaging 50% and 82%, respectively, with a further 100% median growth projected over the next 5 y. Of note, more respondents indicated cognizance of personalized dosimetry than actually used it routinely. The most commonly identified barriers to future growth in PCa theranostics were radiopharmaceutical supply, reimbursement, staff availability, and buy-in of medical oncologists. Conclusion: Despite enthusiasm, this survey indicates variable adoption of PSMA imaging and RLT globally. Several challenges need to be addressed by the medical community, authorities, and patient advocacy groups in integrating PSMA-targeted theranostics into personalized medicine.
DOI:doi:10.2967/jnumed.122.264298
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.2967/jnumed.122.264298
 Volltext: https://jnm.snmjournals.org/content/64/1/47
 DOI: https://doi.org/10.2967/jnumed.122.264298
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:PET
 prostate cancer
 PSMA
 survey
 Theranostics
K10plus-PPN:186638077X
Verknüpfungen:→ Zeitschrift

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